Nazar İleri Ercan

E-mail

nileri@metu.edu.tr

Department

Department of Chemical Engineering

Nanoparticle-induced toxicity in pancreatic cancer: Insights from machine learning models Cakir, Irem; Yildirim, Elif; İleri Ercan, Nazar (2025-12-01) In this study, 83 research articles published between 2008 and 2024 on the effects of various nanoparticles on pancreatic cancer are reviewed, and a dataset of 2696 data points is constructed. The dataset, which is analyze...
Machine Learning Analysis of Cytotoxicity Determinants in Nanoparticle-Based Rheumatoid Arthritis Therapies Yildirim, Elif; Cakir, Irem; İleri Ercan, Nazar (2025-11-03) Nanoparticle-based therapies have gained attention in recent years as promising treatments for rheumatoid arthritis (RA), due to the potential offered for targeted delivery, controlled drug release, and improved biocompati...
Phytochemicals in Pancreatic Cancer Treatment: A Machine Learning Study Genc, Destina Ekingen; Ozbek, Ozlem; Oral, Burcu; Yıldırım, Ramazan; İleri Ercan, Nazar (2024-01-09) The discovery of new strategies and novel therapeutic agents is crucial to improving the current treatment methods and increasing the efficacy of cancer therapy. Phytochemicals, naturally occurring bioactive constituents d...
Coarse-grained modeling of polystyrene-modified CNTs and their interactions with lipid bilayers Gul, Gulsah; Faller, Roland; İleri Ercan, Nazar (2023-05-01) In the present work, we describe Martini3 coarse-grained models of polystyrene and carboxyl-terminated polysty-rene functionalized carbon nanotubes (CNTs) and investigate their interactions with lipid bilayers with and wit...
Polystyrene-modified carbon nanotubes: Promising carriers in targeted drug delivery Gul, Gulsah; Faller, Roland; İleri Ercan, Nazar (2022-11-15) To design drug-delivery agents for therapeutic and diagnostic applications, understanding the mechanisms by which covalently functionalized carbon nanotubes penetrate and interact with cell membranes is of great importance...
Molecular dynamics modeling of polystyrene functionalized carbon nanotubes Gul, Gulsah; Faller, Roland; İleri Ercan, Nazar (2022-02-01)
The Toxicity of Polystyrene-Based Nanoparticles in Saccharomyces cerevisiae Is Associated with Nanoparticle Charge and Uptake Mechanism Ozbek, Ozlem; O. Ulgen, Kutlu; İleri Ercan, Nazar (2021-04-19) Polystyrene latex (PSL) nanoparticles (NPs), 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) liposomes, and hybrid NPs that have different concentrations, sizes, surface charges, and functional groups were used to determin...
Cytotoxicity analysis of nanoparticles by association rule mining Gul, Gulsah; Yildirim, Ramazan; İleri Ercan, Nazar (2021-04-01) Understanding the toxicity behavior of NPs is of great importance to ensure efficient delivery to intracellular targets without causing cytotoxicity, to measure the long-term effects of nanoparticles (NPs), and to predict ...
Fullerene translocation through peroxidized lipid membranes Gul, Gulsah; İleri Ercan, Nazar (2021-02-15) Recent cytotoxicity research suggests that fullerenes can enter the cell and cross the blood-brain barrier. However, the underlying toxicity mechanism behind the penetration of fullerenes through biological membranes is st...
Influence of Fullerenes on Peroxidized Lipid Membranes Gul, Gulsah; İleri Ercan, Nazar (2021-02-01)

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