The functions of cyclin-dependent kinase inhibitors p16(INK4a) and p15(INK4b) in human osteosarcomas

Aytaç, Uğur


Studies on cAMP-dependent protein kinase in sheep liver.
Javed, Masood-ul-Hassan; Özer, İnci; Department of Biological Sciences (1984)
Enhanced recovery of silver from Artvin-Kafkasor ore by microbial treatment
Salameh, M; Özcengiz, Gülay; Atalay, U; Ozbayoglu, G; Alaeddinoglu, NG (1999-06-23)
In the Artvin-Kafkasor ore deposit gold and silver are the main precious metals and are associated with quartz and limonite. In the present investigation, a fungal culture isolated from a mine water was tested under laboratory conditions for its bioleaching potential for enhancing silver recovery prior to cyanidation. The silver recovery was expressed as both the silver dissolved after biotreatment and that recovered after cyanidation following biotreatment. Silver recovery increased as a function of fungal...
The investigation of brain growth retardation in rat fetus
Erdogdu, G; Yavin, E (1999-02-01)
We have investigated the activation of the mitogen-activated protein kinases ERK1 and ERK2 in fetal rat brain following induction of ischemia. This treatment rapidly increases the phosphorylation of MAP kinase levels after induction appears to reach a maximum at 2 hrs recirculation time. The ischemic effect on fetal brain might lead to mitogen-activated protein kinase activation and subsequent protein phosphorylation.
The impact of climate variability on the physical properties of the Black Sea for the period 1971 – 2001
Korkmaz, Muhteşem Akif; Salihoğlu, Barış; Cannaby, Heather Anne; Department of Physical Oceanography (2011)
Deep ventilation of the Black Sea is inhibited by a sharp salinity gradient within the upper water column, resulting in a shallow anoxic interface at around 100 – 200 m depth. Understanding biological and chemical processes within the boundary region between oxic and anoxic waters is fundamental to comprehend the biogeochemical response of the Black Sea to climate forcing. The structure and depth of the chemocline is largely determined by the physical processes which transport surface waters to depth. Here ...
The Effect of physical properties of the ELP-collagen based patterned surfaces on cell attachment and deformation
Antmen, Ezgi; Hasırcı, Vasıf Nejat; Demirci, Utkan; Department of Biology (2013)
Cell and substrate interactions are important in tissue engineering products especially on the behavior of the cells such as adhesion, migration, proliferation, and differentiation. These have been widely studied using substrates with different physical, chemical, and mechanical properties and form. In this study, elastin-like recombinamers (ELRs) were used blended with collagen or only collagen as the surface material. The ELR used in this study has Valine-Proline-Glycine-X-Glycine aminoacid sequences in i...
Citation Formats
U. Aytaç, “The functions of cyclin-dependent kinase inhibitors p16(INK4a) and p15(INK4b) in human osteosarcomas,” Ph.D. - Doctoral Program, Middle East Technical University, 1996.