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Molecular structure, regulation and subcellular distribution of mu opioid receptors during postnatal development
Date
1990-01-01
Author
Szucs, M.
Öktem, Hüseyin Avni
Szuts, V.
Lengyel, I.
Toth, G.
Coscia, C.J.
Wollemann, M.
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Brains of mature and neonatal (P-3) rats were subjected to subcellular fractionation. Light membranes of P-3 contained more [3H]DAGO binding sites (40% of total μ sites vs 16% in adult) with greater sensitivity to GTP. Affinity labelling with [3H]DAGOCK revealed that the major subunit has a molecular weight of about 50 kDa in the synaptic as well as light membrane fractions.
URI
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0025084123&origin=inward
https://hdl.handle.net/11511/107980
Conference Name
The International Narcotics Research Conference
Collections
Department of Biology, Conference / Seminar
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M. Szucs et al., “Molecular structure, regulation and subcellular distribution of mu opioid receptors during postnatal development,” presented at the The International Narcotics Research Conference, 1990, Accessed: 00, 2024. [Online]. Available: https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0025084123&origin=inward.