INDUCED CURRENT MEDICAL ELECTRO-THERMAL IMAGING

2024-1-24
Tanrıverdi, Volkan
Breast tumors generate more metabolic heat than surrounding healthy tissues. However, detecting deep tumors using infrared (IR) imaging is challenging. This study proposes creating induced currents by applying a time-varying magnetic field to the tumorous breast since an additional temperature contrast occurs due to the electrical conductivity and specific heat differences between the tumors and healthy tissues. The main objectives are: 1) to investigate the feasibility of the method for surface and deep tumors with numerical studies and 2) to demonstrate the use of this method through different experiments conducted with phantoms that mimic breast tissues. Tumorous breasts were modeled numerically, and the active and passive modes were simulated in three dimensions. In simulation studies, the induced current altered the temperature contrast on the imaging surface, resulting in a 4 mm increase in tumor detection sensitivity. An 11-turn, 70 mm long solenoid coil was constructed for the experimental studies, and a 20 A current was applied at 745 kHz. A temperature difference of up to 0.4 °C in the tumor location was observed compared with the absence of the tumor. Similarly, a 23-turn multilayer coil was utilized in serial resonance at 755 kHz with a 3.75 A current, and a 0.4 °C temperature difference at the tumor location was observed. It was concluded that the temperature contrast on the body surface changed, and the tumor detection depth increased with the induced currents in breast IR imaging. The proposed method was validated using in vitro experiments.
Citation Formats
V. Tanrıverdi, “INDUCED CURRENT MEDICAL ELECTRO-THERMAL IMAGING,” Ph.D. - Doctoral Program, Middle East Technical University, 2024.