Surface functionalization of additively manufactured Ti6Al4V scaffolds with CaP/ZnO coatings

Date

2025-01-01

Author

Karimi, Nasrin
Atapour, Masoud
Taherizadeh, Aboozar
Ercan, Batur
Galati, Manuela
Saboori, Abdollah

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

57
views

0
downloads

Cite This

A biologically active coating with strong adhesion can improve the inherent bioinert nature of the additively manufactured Ti6Al4V scaffolds. In this research, a calcium phosphate coating containing antibacterial zinc oxide nanoparticles was applied onto the lattice-structured Ti6Al4V scaffolds using the plasma electrolytic oxidation (PEO) method, and its corrosion resistance and in vitro bioactivity were analyzed. The results revealed that the thickness of the CSh (Coat-Short: Scaffold with an approximate porosity size of 2.23 mm and coated) sample coating was approximately 1.8 times thicker that of the coating created on the CL (Coat-Long: Scaffold with an approximate porosity size of 3.74 mm and coated) sample. Zinc oxide nanoparticles in the coating were found to be uniformly dispersed, resulting in a 5.5% reduction in the hydrophilic behavior of the coatings. Moreover, both types of samples, with the reinforcement of the barrier layer, successfully improved the long-term corrosion behavior of the substrate, with a more pronounced effect on the CSh samples. After 14 days of immersion in simulated body fluid, cauliflower-shaped hydroxyapatite deposits were observed across the entire surface of the coatings. MG63 cells on the CSh sample demonstrated a wider spread and greater adhesion compared to other samples. Additionally, the cell viability increased from 83.3 ± 4.1 (% control) in the uncoated sample to 94.9 ± 1.1 (% control). These results suggest that coatings fabricated on scaffold surfaces with smaller porosity (CSh) exhibit more favorable corrosion and biological behavior, highlighting their potential applications in orthopedics.

Subject Keywords

Additive manufacturing, Calcium phosphate, Plasma electrolytic oxidation, Scaffold, Ti6Al4V, Zinc oxide

URI

https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105004344169&origin=inward
https://hdl.handle.net/11511/114808

Collections

Department of Metallurgical and Materials Engineering, Article