Cihangir Tanyeli

E-mail
tanyeli@metu.edu.tr
Department
Department of Chemistry
Scopus Author ID
The synthesis of chiral β-naphthyl-β-sulfanyl ketones via enantioselective sulfa-Michael reaction in the presence of a bifunctional cinchona/sulfonamide organocatalyst
Tözendemir, Deniz; Tanyeli, Cihangir (2021-02-01)
Cinchona alkaloid-derived organocatalysts are widely employed in various asymmetric transformations, yielding products with high enantiopurity. In this respect, a bifunctional quinine-derived sulfonamide organocatalyst was...
Bifunctional squaramide catalyzed stereoselective Mannich reaction of alpha-azido ketones with isatin-derived ketimines
KARAHAN, SEDA; Tanyeli, Cihangir (Royal Society of Chemistry (RSC), 2020-01-21)
Asymmetric organocatalytic Mannich reaction of alpha-azido ketones and N-Boc protected isatin-derived ketimines were investigated for the first time. Examination of both 2-adamantyl and 3,5-bis(trifluoromethyl)aniline subs...
Squaramide catalyzed alpha-chiral amine synthesis
Karahan, SEDA; Tanyeli, Cihangir (2018-10-17)
Enantiomerically pure alpha-chiral amines, have been commonly utilized as resolving agents and chiral auxiliaries and are currently found in 40% of active pharmaceutical ingredients. Hence, development of highly stereosele...
Enantioselective sulfa-Michael addition reaction of methyl thioglycolate to chalcones derivatives with sterically encumbered quinine squaramide organocatalyst
HASILCIOĞULLARI, DENİZ; Tanyeli, Cihangir (2018-04-04)
Asymmetric organocatalytic sulfa-Michael reactions give access to enantiomerically enriched sulfur containing adducts that can be used as valuable chiral building blocks. A variety of chalcone derivatives were allowed to r...
Asymmetric organocatalytic direct Mannich reaction of acetylacetone and isatin derived ketimines: Low catalyst loading in chiral cinchona-squaramides
İŞİBOL, Duygu; Karahan, SEDA; Tanyeli, Cihangir (2018-02-07)
A highly enantioselective synthesis of 3-amino-2-oxindoles by direct Mannich reaction between acetylacetone and N-carbamoyl isatin ketimine has been described herein. Corresponding chiral adducts were obtained in high yiel...
Organocatalytic enantioselective construction of isatin-derived N-alkoxycarbonyl 1,3-aminonaphthols via sterically encumbered hydrocarbon-substituted quinine-based squaramide
Karahan, SEDA; Tanyeli, Cihangir (2017-09-07)
Herein, an illustrative example to synthesize chiral naphthoxazepine precursors via the aza-Friedel-Crafts reaction of N-alkoxycarbonyl isatin ketimines with naphthol using a new 2-adamantyl-substituted quinine-derived squ...
Enantioselective aza-Henry reaction of t-Boc protected imines and nitroalkanes with bifunctional squaramide organocatalysts
Susam, Zeynep Dilşad; Tanyeli, Cihangir (2017-05-07)
An organocatalytic asymmetric aza-Henry reaction of t-Boc protected imines with nitroalkanes has been established by chiral acid-base type bifunctional Cinchona alkaloid/squaramide organocatalysts. The cooperation of a qui...
Asymmetric organocatalytic Michael additions of methyl thioglycolate to various acceptors
Tözendemir, Deniz; Tanyeli, Cihangir (2017-04-06)
Divergent synthesis of polysubstituted isoxazoles, isoxazoline N-oxides, and dihydroisoxazoles by a one-pot cascade reaction
Rouf, Abdul; ŞAHİN, Ertan; Tanyeli, Cihangir (Elsevier BV, 2017-01-26)
An efficient one-pot synthesis of a new class of 3,4,5-trisubstituted isoxazoline N-oxides/isoxazoles and dihydroisoxazoles is developed by a green approach from aromatic and aliphatic aldehydes by controlling the reaction...
Squaramide Based Organocatalysts in Organic Transformations
Rouf, Abdul; Tanyeli, Cihangir (2016-12-01)
Organocatalysis is an emerging and new field towards the direction of asymmetric synthesis and has shown a tremendous growth in 21st century. As the demand for chiral pharmaceuticals and chiral organic molecules is increas...