Çağdaş Devrim Son

E-mail

cson@metu.edu.tr

Department

Department of Biology

ORCID

0000-0002-4076-5441

Scopus Author ID

7005976995

Web of Science Researcher ID

C-8018-2014

A New Ratio-Metric pH Probe, "ThiAKS Green" for Live-Cell pH Measurements Akyol, Ali; Baykal, Doruk; Akdağ, Akın; Sensoy, Ozge; Son, Çağdaş Devrim (2023-3-01) Deviation of the H+ concentration from optimum values within the organelles is closely associated with irregular cellular functions that cause the onset of various diseases. Therefore, determining subcellular pH values in ...
Downstream signalling of the disease-associated mutations on GPR56/ADGRG1 CEVHEROĞLU, ORKUN; Demir, Nil; Kesici, Mehmet Seçkin; Özçubukçu, Salih; Son, Çağdaş Devrim (2023-01-01) GPR56/ADGRG1 is an adhesion G protein-coupled receptor (GPCR) and mutations on this receptor cause cortical malformation due to the over-migration of neural progenitor cells on brain surface. At pial surface, GPR56 interac...
Somatic copy number variant load in neurons of healthy controls and Alzheimer’s disease patients Turan, Zeliha Gözde; Richter, Vincent; Bochmann, Jana; Parvizi, Poorya; Yapar, Etka; Işıldak, Ulas; Waterholter, Sarah-Kristin; Leclere-Turbant, Sabrina; Son, Çağdaş Devrim; Duyckaerts, Charles; Yet, İdil; Arendt, Thomas; Somel, Mehmet; Ueberham, Uwe (2022-12-01) The possible role of somatic copy number variations (CNVs) in Alzheimer’s disease (AD) aetiology has been controversial. Although cytogenetic studies suggested increased CNV loads in AD brains, a recent single-cell whole-g...
Fast Screening of Protein-Protein Interactions Using Forster Resonance Energy Transfer (FRET-) Based Fluorescence Plate Reader Assay in Live Cells Durhan, Seyda Tugce; Sezer, Enise Nalli; Son, Çağdaş Devrim; Küçük Baloğlu, Fatma (2022-11-01) Protein-protein interactions (PPIs) have great importance for intracellular signal transduction and sustaining the homeostasis of an organism. Thus, the identification of PPIs is necessary to better understand the downstre...
SMN loss dysregulates microtubule-associated proteins in spinal muscular atrophy model Zobaroğlu Özer, Pelin; Koyunoğlu, Dila; Son, Çağdaş Devrim; Erdem-Yurter, Hayat Erdem; BORA, GAMZE (2022-05-01) © 2022 Elsevier Inc.Spinal muscular atrophy (SMA) is a rare neurodegenerative disease caused by the absence of survival motor neuron (SMN) protein. SMN loss results in impairments of the cytoskeleton, including microtubule...
Ste2p Under the Microscope: the Investigation of Oligomeric States of a Yeast G Protein-Coupled Receptor CEVHEROĞLU, ORKUN; Murat, Merve; Mingu-Akmete, Sara; Son, Çağdaş Devrim (2021-08-01) Oligomerization of G protein-coupled receptors (GPCRs) may play important roles in maturation, internalization, signaling, and pharmacology of these receptors. However, the nature and extent of their oligomerization is sti...
Allergen fragrance molecules: a potential relief for COVID-19 Aydin, Asli Deniz; Altinel, Faruk; Erdogmus, Hueseyin; Son, Çağdaş Devrim (2021-01-01) BackgroundThe latest coronavirus SARS-CoV-2, discovered in China and rapidly spread Worldwide. COVID-19 affected millions of people and killed hundreds of thousands worldwide. There are many ongoing studies investigating d...
The behaviour of neuro-2A cells on silicon substrates with various topographies generated by femtosecond laser micromachining Mingu, Sara; Pavlov, Ihor; Son, Çağdaş Devrim; Bek, Alpan (2020-01-01)
Oligomerization and cell surface expression of recombinant GABA(A) receptors tagged in the delta subunit Oflaz, Furkan Enes; Son, Çağdaş Devrim; Arslan, Ayla (IMR Press, 2019-12-01) The gamma-Aminobutyric acid type A receptors (GABA(A) Rs) are heteropentameric chloride channels responsible for primary inhibition in the mammalian brain. Studies have shown the expression of recombinant GABA(A) R subunit...
In vitro SMA Modelinde Mikrotübül Pozitif Uç Proteinlerinin Araştırılması Koyunoğlu, Dila; Bora, Gamze; Son, Çağdaş Devrim; Yurter, Hayat (null; 2019-11-01)

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