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Mürvet Volkan

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Development of a solid-phase microextraction LC-MS/MS method for determination of oxidative stress biomarkers in biofluids
Kahremanoglu, Kubra; Temel, Ezgi Rana; Korkut, Tamara Ecem; Nalbant, Atakan Arda; Baştuğ Azer, Bersu; Durucan, Caner; Volkan, Mürvet; Boyacı, Ezel (Wiley, 2020-04-03)
Recently the connection between oxidative stress and various diseases, including cancer and Alzheimer's, attracts notice as a pathway suitable for diagnostic purposes. 8-Oxo-deoxyguanosine and 8-oxo-deoxyadenosine produced...
EF2-kinase targeted cobalt-ferrite siRNA-nanotherapy suppresses BRCA1-mutated breast cancer
Asik, Elif; Akpinar, Yeliz; Caner, Ayse; Kahraman, Nermin; Güray, Nülüfer Tülün; Volkan, Mürvet; Albarracins, Constance; Pataer, Apar; Arun, Banu; Ozpolat, Bulent (Future Medicine Ltd, 2019-09-01)
Aim: To investigate the role of EF2K in BRCA1-mutated breast cancer. Materials & methods: We developed silica coated cobalt-ferrite (CoFe) nanoparticles for in vivo delivery of small interfering RNAs (siRNAs) into BRCA1-mu...
Gold-assembled silica-coated cobalt nanoparticles as efficient magnetic separation units and surface-enhanced Raman scattering substrate
Yıldırım, Lütfiye Sezen; KAYA, MURAT; Volkan, Mürvet (The Scientific and Technological Research Council of Turkey, 2019-01-01)
Magnetic and optical bifunctional nanoparticles that combine easy separation, preconcentration, and efficient SERS capabilities have been fabricated with high sensitivity and reproducibility through a low-cost method. Thes...
Cellular uptake and apoptotic potential of rhenium labeled magnetic protein cages in MDA-MB-231 cells
Asik, Elif; Aslan, Tugba Nur; Güray, Nülüfer Tülün; Volkan, Mürvet (Elsevier BV, 2018-10-01)
Re-188-magnetoferritin nanoparticles (NPs) provide an attractive platform for localized radiation therapy due to their magnetic targeting capability while enhancing contrast in magnetic resonans imaging (MRI) signals. In t...
Selenium speciation in chicken breast samples from inorganic and organic selenium fed chickens using high performance liquid chromatography-inductively coupled plasma-mass spectrometry
BAKIRDERE, Sezgin; Volkan, Mürvet; Ataman, Osman Yavuz (2018-08-01)
Speciation of selenium in chicken breast samples was performed by anion and cation exchange HPLC systems combined with ICP-MS. Samples were categorized into three groups consisting of Control Group, Inorganic Se Fed Group ...
Eucaryotic elongation factor 2kinaze is a novel therapeutic target in BRCA1 mutated breast cancer
Volkan, Mürvet; Güray, Nülüfer Tülün; Asik, Elif; Lopez-Berestein, Gabriel; Ozpolat, Bulent; Kahraman, Nermin (2017-07-01)
A Novel Acetylcholinesterase Biosensor: Core-Shell Magnetic Nanoparticles Incorporating a Conjugated Polymer for the Detection of Organophosphorus Pesticides
Cancar, Hurija Dzudzevic; SÖYLEMEZ, Saniye; AKPINAR, Yeliz; KESİK, Melis; Goker, SEZA; Günbaş, Emrullah Görkem; Volkan, Mürvet; Toppare, Levent Kamil (American Chemical Society (ACS), 2016-03-30)
To construct a sensing interface, in the present work, a conjugated polymer and core shell magnetic nano particle containing biosensor was constructed for the pesticide analysis. The monomer 4,7-di(furan-2-yl)benzo [c] [1,...
Cellular uptake, genotoxicity and cytotoxicity of cobalt ferrite magnetic nanoparticles in human breast cells
Asik, Elif; Akpinar, Yeliz; Güray, Nülüfer Tülün; Iscan, Mesude; ÇAKMAK DEMİRCİGİL, GONCA; Volkan, Mürvet (Oxford University Press (OUP), 2016-01-01)
Magnetic nanoparticles (MNPs) have been increasingly used for many years as MRI agents and for gene delivery and hyperthermia therapy, although there have been conflicting results on their safety. In this study, cobalt fer...
Preparation and labeling of surface-modified magnetoferritin protein cages with a rhenium(I) carbonyl complex for magnetically targeted radiotherapy
Aslan, Tugba Nur; Asik, Elif; Volkan, Mürvet (Royal Society of Chemistry (RSC), 2016-01-01)
New rhenium radiolabeled compounds are of general interest due to their nuclear characteristics which allow radiotherapy and in situ monitoring of tumor uptake. Biocompatible magnetic nanoparticles capable of transporting ...
2-Amino-2-deoxy-glucose conjugated cobalt ferrite magnetic nanoparticle (2DG-MNP) as a targeting agent for breast cancer cells
Asik, Elif; Aslan, Tugba Nur; Volkan, Mürvet; Güray, Nülüfer Tülün (2016-01-01)
In this study, 2-amino-2-deoxy-glucose (2DG) was conjugated to COOH modified cobalt ferrite magnetic nanoparticles (COOH-MNPs), which were designed to target tumor cells as a potential targetable drug/gene delivery agent f...