Başak Kayaoğlu

E-mail
btoygar@metu.edu.tr
Department
Department of Biology
Scopus Author ID
Web of Science Researcher ID
DOCK8 deficiency with hypereosinophilia and the syndrome of inappropriate antidiuretic hormone secretion during herpes infection
Yeşil, Ayşe Mete; Kayaoğlu, Başak; Gül, Ersin; Gönç, Nazlı; Özön, Alev; Tezcan, İlhan; Gürsel, Mayda; ÇAĞDAŞ AYVAZ, DENİZ NAZİRE (2023-01-01)
Background. Hyperimmunoglobulin E syndrome (HIES) due to dedicator of cytokinesis8 (DOCK8) deficiency may present in infancy and childhood with different clinical features involving recurrent infections, allergic dysregula...
Expanding the Clinical and Immunological Phenotypes and Natural History of MALT1 Deficiency
Sefer, Asena Pinar; et. al. (2022-01-01)
Purpose MALT1 deficiency is a combined immune deficiency characterized by recurrent infections, eczema, chronic diarrhea, and failure to thrive. Clinical and immunological characterizations of the disease have not been pre...
Low Density Granulocytes and Dysregulated Neutrophils Driving Autoinflammatory Manifestations in NEMO Deficiency
Yilmaz, Naz Surucu; et. al. (2022-01-01)
NF-kappa B essential modulator (NEMO, IKK-gamma) deficiency is a rare combined immunodeficiency caused by mutations in the IKBKG gene. Conventionally, patients are afflicted with life threatening recurrent microbial infect...
Development and preclinical evaluation of virus-like particle vaccine against COVID-19 infection
YILMAZ, İSMAİL CEM; et. al. (2021-09-01)
Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes the development and immunogenicity of SARS-CoV-2 VLP v...
Stepwise Reversal of Immune Dysregulation Due to STAT1 Gain-of-Function Mutation Following Ruxolitinib Bridge Therapy and Transplantation
Kayaoğlu, Başak; Yilmaz, Naz Surucu; Charbonnier, Louis Marie; Geckin, Busranur; Akcay, Arzu; Eltan, Sevgi Bilgic; Ozturk, Gulyuz; ÖZEN, AHMET OĞUZHAN; Karakoc-Aydiner, Elif; Chatila, Talal A.; Gürsel, Mayda (2021-01-01)
Purpose Patients with heterozygous gain-of-function (GOF) mutations in STAT1 frequently exhibit chronic mucocutaneous candidiasis (CMC), immunodeficiency and autoimmune manifestations. Several treatment options including t...
Type I IFN-related NETosis in ataxia telangiectasia and Artemis deficiency
Gul, Ersin; et. al. (2018-07-01)
Background: Pathological inflammatory syndromes of unknown etiology are commonly observed in ataxia telangiectasia (AT) and Artemis deficiency. Similar inflammatory manifestations also exist in patients with STING-associat...
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