Elif Serel Yılmaz

E-mail

serel@metu.edu.tr

Department

Department of Chemistry

ORCID

0000-0001-7541-1507

Scopus Author ID

57219151519

Web of Science Researcher ID

ABD-7965-2021

Facile synthesis of unknown 6,7-dihydrofuro[3,4-c]pyridines and 3,4-diaryloylpyridines from N-homopropargylic β-enaminones Yılmaz, Elif Serel; Kaya, Kerem; Zora, Metin (2025-01-01) In this paper, we have uncovered a new reaction of N-homopropargylic β-enaminones, i.e. N-(4-phenyl-3-butynyl)-β-enaminones. When subjected to a reaction with excess molecular iodine or N-iodosuccinimide in the presence of...
Novel Enyne-Modified 1,4-Thiazepines as Epidermal Growth Factor Receptor Inhibitors: Anticancer and Computational Studies Atmaca, Harika; Pulat, Cisil Camli; Ilhan, Suleyman; Yılmaz, Elif Serel; Zora, Metin (2024-12-26) 1,4-Thiazepines (TZEPs) featuring enyne modifications represent promising candidates in cancer therapy. We synthesized novel TZEP derivatives and assessed their cytotoxicity, apoptosis induction, EGFR inhibition, and molec...
N-Propargylic β-enaminones in breast cancer cells: Cytotoxicity, apoptosis, and cell cycle analyses Ilhan, Suleyman; Atmaca, Harika; Yılmaz, Elif Serel; YILDIZ, ESRA; Zora, Metin (2023-01-01) Breast cancer is one of the most common cancers worldwide and the discovery of new cytotoxic agents is needed. Enaminones are regarded to be a significant structural motif that is found in a variety of pharmacologically ac...
4-Propargyl-substituted 1H-pyrroles induce apoptosis and autophagy via extracellular signal-regulated signaling pathway in breast cancer Atmaca, Harika; Ilhan, Suleyman; Yılmaz, Elif Serel; Zora, Metin (2021-01-01) Novel pyrrole derivatives (PDs) with propargyl units (1–7) were investigated for their anticancer activity on breast cancer cells. The MTT assay was used to assess the cell viability. Morphological changes in human breast ...
A facile one-pot synthesis of 2-(prop-2-yn-1-ylidene)-2,3-dihydro-1,4-thiazepines Yılmaz, Elif Serel; Zora, Metin (Informa UK Limited, 2020-11-01) An unprecedented method for the synthesis of 2-(prop-2-yn-1-ylidene)-2,3-dihydro-1,4-thiazepines from N-(2,4-pentadiynyl) beta-enaminones is reported. Upon treatment with Lawesson's reagent, N-(2,4-pentadiynyl) beta-enamin...
A New Strategy for the Synthesis of 4-Propargyl-Substituted 1H-Pyrroles from N-(5-phenyl-2,4-pentadiynyl) beta-Enaminones Yılmaz, Elif Serel; Zora, Metin (2019-10-09) A new method for the synthesis of 4-propargyl-substituted 1H-pyrroles is described. When treated with sodium hydride in refluxing dichloromethane, N-(5-phenyl-2,4-pentadiynyl) beta-enaminones, synthesized by the coupling o...
N-Proparjilik β-Enaminon Bileşiklerinden Proparjil Sübstitüye Pirol Türevlerinin Sentezi Yılmaz, Elif Serel; Zora, Metin (2017-10-14)
Synthesis of propargyl-substituted pyrroles Yılmaz, Elif Serel; Zora, Metin (2017-04-02)
Synthesis of alkynyl substituted pyrroles Yılmaz, Elif Serel; Zora, Metin (2016-03-21)

Citation Formats