Erkan Kiriş

E-mail
ekiris@metu.edu.tr
Department
Department of Biology
Scopus Author ID
Web of Science Researcher ID
TrkA-cholinergic signaling modulates fear encoding and extinction learning in PTSD-like behavior.
Yanpallewar, Sudhirkumar; Tomassoni-Ardori, Francesco; Palko, Mary Ellen; Hong, Zhenyi; Kiriş, Erkan; Becker, Jodi; Fulgenzi, Gianluca; Tessarollo, Lino (2022-03-17)
Recent studies have suggested that the use of cognitive enhancers as adjuncts to exposure-based therapy in individuals suffering from post-traumatic stress disorder (PTSD) may be beneficial. Brain cholinergic signaling thr...
Human-Induced Pluripotent Stem Cell-Based Models for Studying Sex-Specific Differences in Neurodegenerative Diseases.
Kiriş, Erkan (2021-12-19)
Amyloid beta peptit oligomerlerinin (Aβ(1-42)) in vitro muamelesinin TrkB sinyali artırılmış kök hücre temelli kortikal nöronlar üzerindeki etkisinin doğal kortikal nöronlar ile kıyaslamalı olarak araştırılması
Beşarat, Peri; Ezgin, Sena; Kiriş, Erkan (2021-11-22)
Fare Kök Hücrelerinden Başkalaştırılmış Bazal Ön Beyin Kolinerjik Nöronlarda TrkA Sinyalinin Artırılmasının in vitro Alzheimer Hastalığını Nörodejeneratif Sürecine Karşı Etkisinin Kontrollere Kıyasla Araştırılması
Ezgin, Sena; Kiriş, Erkan (2021-11-22)
Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity.
Sen, Edanur; Kota, Krishna P; Panchal, Rekha G; Bavari, Sina; Kiriş, Erkan (2021-09-27)
Generation and characterization of human induced pluripotent stem cell line METUi001-A from a 25-year-old male patient with relapsing-remitting multiple sclerosis
Koc, Dilara; Begentaş, Onur Can; Yurtogullari, Sukran; Temel, Musa; Akcali, Kamil Can; Demirkaya, Seref; Kiriş, Erkan (2021-05-01)
Multiple sclerosis is a chronic disease characterized by inflammation, demyelination, and axonal damage in the central nervous system. Here, we established an induced pluripotent stem cell (iPSC) line METUi001-A from the p...
MS’de Kök Hücre Temelli Moleküler Mekanizma Çalışmaları
Kiriş, Erkan (2020-02-16)
New Steroidal 4-Aminoquinolines Antagonize Botulinum Neurotoxin Serotype A in Mouse Embryonic Stem Cell Derived Motor Neurons in Postintoxication Model.
Konstantinović, J; Kiriş, Erkan; Kota, KP; Kugelman-Tonos, J; Videnović, M; Cazares, LH; Terzić, Jovanović; Verbić, TŽ; Andjelković, B; Duplantier, AJ; Bavari, S; Šolaja, BA (American Chemical Society (ACS), 2018-02-22)
The synthesis and inhibitory potencies against botulinum neurotoxin serotype A light chain (BoNT/A LC) using in vitro HPLC based enzymatic assay for various steroidal, benzothiophene, thiophene, and adamantane 4-aminoquino...
Deubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxication.
Tsai, YC; Kotiya, A; Kiriş, Erkan; Yang, M; Bavari, S; Tessarollo, L; Oyler, GA; Weissman, AM (2017-06-27)
Botulism is characterized by flaccid paralysis, which can be caused by intoxication with any of the seven known serotypes of botulinum neurotoxin (BoNT), all of which disrupt synaptic transmission by endoproteolytic cleava...
Paclitaxel suppresses Tau-mediated microtubule bundling in a concentration-dependent manner.
Choi, MC; Chung, PJ; Song, C; Miller, HP; Kiriş, Erkan; Li, Y; Wilson, L; Feinstein, SC; Safinya, CR (2017-01-01)
Background: Microtubules (MTs) are protein nanotubes comprised of straight protofilaments (PFs), head to tail assemblies of alpha beta-tubulin heterodimers. Previously, it was shown that Tau, a microtubule-associated prote...
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