Mehmet Somel

E-mail
msomel@metu.edu.tr
Department
Department of Biology
Scopus Author ID
Web of Science Researcher ID
Human inbreeding has decreased in time through the Holocene
Ceballos, Francisco C.; Gürün, Kanat; Altınışık, Nefize Ezgi; Gemici, Hasan Can; Karamurat, Cansu; Koptekin, Dilek; Vural, Kıvılcım Başak; Mapelli, Igor; Sağlıcan, Ekin; Sürer, Elif; Erdal, Yılmaz Selim; Götherström, Anders; Özer, Füsun; Atakuman, Çiğdem; Somel, Mehmet (2021-07-01)
Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes
Yaka, Reyhan; et. al. (2021-06-01)
Million-year-old DNA sheds light on the genomic history of mammoths
van der Valk, Tom; et. al. (Springer Science and Business Media LLC, 2021-2-17)
Temporal genomic data hold great potential for studying evolutionary processes such as speciation. However, sampling across speciation events would, in many cases, require genomic time series that stretch well back into th...
Human population dynamics and Yersinia pestis in ancient northeast Asia
Kilinc, Gulsah Merve; et. al. (2021-01-01)
We present genome-wide data from 40 individuals dating to c.16,900 to 550 years ago in northeast Asia. We describe hitherto unknown gene flow and admixture events in the region, revealing a complex population history. Whil...
Ancient genomics in Neolithic Central Anatolia and Çatalhöyük
Yaka, Reyhan; Doğu, Ayça; Kaptan, Damla; Dağtaş, Nihan Dilşad; Chyleński, Maciej; Vural, Kıvılcım Başak; Altınışık, Nefize Ezgi; Mapelli, Igor; Koptekin, Dilek; Karamurat, Cansu; Gemici, Hasan Can; Yorulmaz, Sevgi; Lagerholm, Vendela Kempe; Fer, Evrim; Işıldak, Ulaş; Ghalichi, Ayshin; Kılınç, Gülşah Merve; Mazzucato, Camilla; Juras, Anna; Marciniak, Arkadiusz; Larsen, Clark S.; Pilloud, Marin; Haddow, Scott D.; Knüsel, Christopher J.; Togan, İnci; Götherström, Anders; Erdal, Yılmaz Selim; Sürer, Elif; Özer, Füsun; Atakuman, Çiğdem; Somel, Mehmet (British Institute of Archaeology at Ankara, 2021-01-01)
Over multiple millennia, from the earliest traces of long-term occupation of camp sites (ca 20,000 BC) to the development of full-scale farming (ca 8000–6000 BC), the Neolithic transition in southwest Asia gradually shaped...
Benchmarking kinship estimation tools for ancient genomes using pedigree simulations
Çetin, Mehmet; Aktürk, Şevval; Mapelli, Igor; Yaka, Reyhan; Çokoğlu, Seda; Zakaria, Douaa; Ceballos, Francisco; Ghalichi, Ayshin; Altınışık, N. Ezgi; Koptekin, Dilek; Vural, Kıvılcım Başak; Erdal, Yılmaz Selim; Atakuman, Çiğdem; Götherström, Anders; Özer, Füsun; Sürer, Elif; Somel, Mehmet (2020-10-22)
There is growing interest in identifying genetic kinship levels among ancient individuals buried in physical proximity, from graveyards to archaeological crime scenes. Ancient genome data produced using massively parallel ...
Temporal changes in the gene expression heterogeneity during brain development and aging
Isildak, Ulas; Somel, Mehmet; Thornton, Janet M.; Donertas, Handan Melike (Springer Science and Business Media LLC, 2020-03-01)
Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased variability between cells and individuals over time. Although increased interindividual hete...
Ancient genomics in Anatolia: challenges and opportunities
Somel, Mehmet (null; 2019-10-19)
The increasing availability of ancient genomes has been accelerating studies in a number of fields, including human history, molecular evolution, and conservation biology. The METU/Hacettepe Ancient DNA Group has been cont...
Discovery of Structural Variations in Ancient Genomes
Söylev, Arda; Alkan, Can; Somel, Mehmet (2019-10-17)
Molecular footprint of Medawar's mutation accumulation process in mammalian aging
Turan, Zeliha Gozde; Parvizi, Poorya; Donertas, Handan Melike; Tung, Jenny; Khaitovich, Philipp; Somel, Mehmet (2019-08-01)
Medawar's mutation accumulation hypothesis explains aging by the declining force of natural selection with age: Slightly deleterious germline mutations expressed in old age can drift to fixation and thereby lead to aging-r...
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