Mehmet Somel

Department of Biology
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Variable kinship patterns in Neolithic Anatolia revealed by ancient genomes
Yaka, Reyhan; et. al. (2021-06-01)
Million-year-old DNA sheds light on the genomic history of mammoths
van der Valk, Tom; et. al. (Springer Science and Business Media LLC, 2021-2-17)
Temporal genomic data hold great potential for studying evolutionary processes such as speciation. However, sampling across speciation events would, in many cases, require genomic time series that stretch well back into th...
Human population dynamics and Yersinia pestis in ancient northeast Asia
Kilinc, Gulsah Merve; et. al. (2021-01-01)
We present genome-wide data from 40 individuals dating to c.16,900 to 550 years ago in northeast Asia. We describe hitherto unknown gene flow and admixture events in the region, revealing a complex population history. Whil...
Temporal changes in the gene expression heterogeneity during brain development and aging
Isildak, Ulas; Somel, Mehmet; Thornton, Janet M.; Donertas, Handan Melike (Springer Science and Business Media LLC, 2020-03-01)
Cells in largely non-mitotic tissues such as the brain are prone to stochastic (epi-)genetic alterations that may cause increased variability between cells and individuals over time. Although increased interindividual hete...
Ancient genomics in Anatolia: challenges and opportunities
Somel, Mehmet (null; 2019-10-19)
The increasing availability of ancient genomes has been accelerating studies in a number of fields, including human history, molecular evolution, and conservation biology. The METU/Hacettepe Ancient DNA Group has been cont...
Molecular footprint of Medawar's mutation accumulation process in mammalian aging
Turan, Zeliha Gozde; Parvizi, Poorya; Donertas, Handan Melike; Tung, Jenny; Khaitovich, Philipp; Somel, Mehmet (2019-08-01)
Medawar's mutation accumulation hypothesis explains aging by the declining force of natural selection with age: Slightly deleterious germline mutations expressed in old age can drift to fixation and thereby lead to aging-r...
Ancient Mitochondrial Genomes Reveal the Absence of Maternal Kinship in the Burials of catalhoyuk People and Their Genetic Affinities
Chylenski, Maciej; Ehler, Edvard; Somel, Mehmet; Yaka, Reyhan; Krzewinska, Maja; Dabert, Miroslawa; Juras, Anna; Marciniak, Arkadiusz (MDPI AG, 2019-03-11)
catalhoyuk is one of the most widely recognized and extensively researched Neolithic settlements. The site has been used to discuss a wide range of aspects associated with the spread of the Neolithic lifestyle and the soci...
An Archaeogenomic Investigation of Consanguinity During the Neolithic Transition
Taskent, Recep O.; Sumer, Arev P.; Koptekin, Dilek; Ozkan, Mustafa; Ceballos, Francisco C.; Gokcumen, Omer; Somel, Mehmet (2019-03-01)
Genomic and Strontium Isotope Variation Reveal Immigration Patterns in a Viking Age Town
Krzewinska, Maja; Kjellstrom, Anna; Guenther, Torsten; Hedenstierna-Jonson, Charlotte; Zachrisson, Torun; Omrak, Ayca; Yaka, Reyhan; Kilinc, Gulsah Merve; Somel, Mehmet; Sobrado, Veronica; Evans, Jane; Knipper, Conine; Jakobsson, Mattias; Stora, Jan; Gotherstrom, Anders (Elsevier BV, 2018-09-10)
The impact of human mobility on the northern European urban populations during the Viking and Early Middle Ages and its repercussions in Scandinavia itself are still largely unexplored. Our study of the demographics in the...
Investigating Holocene human population history in North Asia using ancient mitogenomes
Kilinc, Gulsah Merve; et. al. (Springer Science and Business Media LLC, 2018-06-12)
Archaeogenomic studies have largely elucidated human population history in West Eurasia during the Stone Age. However, despite being a broad geographical region of significant cultural and linguistic diversity, little is k...
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