Mehmet Seçkin Kesici

E-mail
skesici@metu.edu.tr
Department
Department of Chemistry
Scopus Author ID
Web of Science Researcher ID
Highly Potent Peptide Therapeutics To Prevent Protein Aggregation in Huntington’s Disease
Khan, Anooshay; Özçelik, Cemile Elif; Begli, Ozge; Oguz, Oguzhan; Kesici, Mehmet Seçkin; Kasırga, Talip Serkan; Özçubukçu, Salih; YÜCA YILMAZ, Esra; Seker, Urartu Ozgur Safak (2023-01-01)
Huntington’s disease (HD) is a neurodegenerative disorder resulting from a significant amplification of CAG repeats in exon 1 of the Huntingtin (Htt) gene. More than 36 CAG repeats result in the formation of a mutant Htt (...
Downstream signalling of the disease-associated mutations on GPR56/ADGRG1
CEVHEROĞLU, ORKUN; Demir, Nil; Kesici, Mehmet Seçkin; Özçubukçu, Salih; Son, Çağdaş Devrim (2023-01-01)
GPR56/ADGRG1 is an adhesion G protein-coupled receptor (GPCR) and mutations on this receptor cause cortical malformation due to the over-migration of neural progenitor cells on brain surface. At pial surface, GPR56 interac...
Poly(2-ethyl-2-oxazoline-co-ethyleneimine)-block-poly(epsilon-caprolactone) based micelles: synthesis, characterization, peptide conjugation and cytotoxic activity
Gulyuz, Sevgi; Ozkose, Umut Ugur; Khalily, Melek Parlak; Kesici, Mehmet Seçkin; Kocak, Polen; Bolat, Zeynep Busra; Kara, Aslı; Öztürk, Naile; Özçubukçu, Salih; Bozkır, Asuman; Alptürk, Onur; Telci, Dilek; Şahin, Fikrettin; Vural, Imran; Yilmaz, Ozgur (2021-07-01)
Here we present self-assembled polymeric micelles as potential delivery systems for therapeutic agents with highly tunable properties. The major goal of this study is to design breast and prostate cancer specific targeting...
Development of Chlorotoxin Peptide-Based Matrix Metalloproteinase-2 Inhibitors
Kesici, Mehmet Seçkin; Güleç, Ezgi; Özen, Can; Özçubukçu, Salih (null; 2017-06-22)
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