Emre Mert İpekoğlu

E-mail

memre@metu.edu.tr

Department

Department of Biology

ORCID

0000-0003-3104-7509

Scopus Author ID

57192423745

Web of Science Researcher ID

AAZ-9259-2020

A phase I/II study of CpG/alum-adjuvanted mammalian-derived quadruple antigen carrying virus-like particle COVID-19 vaccine Yilmaz, Ismail Cem; İpekoğlu, Emre Mert; Golcuklu, Berfu Saraydar; Bildik, Tugce; Aksoy, Aslı Gulce Bartan; Evcili, Irem; Turay, Nilsu; Surucu, Naz; Bulbul, Artun; Guvencli, Nese; Yildirim, Muzaffer; Canavar Yildirim, Tugce; Atalay, Yagmur Aydin; Abras, Irem; Ceylan, Yasemin; Ozsurekci, Yasemin; Tigen, Elif Tukenmez; Korten, Volkan; Gürsel, Mayda; Gursel, Ihsan (2025-03-07) Background: Waning Spike-elicited immunity and emerging COVID-19 variants underscore the need for vaccines leveraging multiple SARS-CoV-2 antigens, rapidly adaptable to evolving strains. Herein, we evaluated the safety and...
Plasma Extracellular Vesicles Derived from Pediatric COVID-19 Patients Modulate Monocyte and T Cell Immune Responses Based on Disease Severity Cetinkaya, Pınar Gur; Abras, Irem Fatma; Evcili, Irem; Yildirim, Tugçe; Ceylan, Yasemin; Kara Eroglu, Fehime; Kayaoğlu, Başak; İpekoğlu, Emre Mert; Akarsu, Aysegul; Yıldırım, Muzaffer; Kahraman, Tamer; Cengiz, Ali Bülent; Sahiner, Umit Murat; Sekerel, Bulent Enis; Ozsurekci, Yasemin; Soyer, Ozge; Gursel, Ihsan (2024-01-01) Background: The COVID-19 pandemic has caused significant morbidity and mortality globally. The role of plasma-derived extracellular vesicles (EVs) in pediatric COVID-19 patients remains unclear. Methods: We isolated EVs fr...
Leishmania kinetoplast DNA contributes to parasite burden in infected macrophages: Critical role of the cGAS-STING-TBK1 signaling pathway in macrophage parasitemia Yilmaz, Ismail Cem; Dünüroğlu, Emre; Ayanoğlu, İhsan Cihan; İpekoğlu, Emre Mert; Yildirim, Muzaffer; GİRGİNKARDEŞLER, NOGAY; ÖZBEL, YUSUF; TÖZ, SERAY; ÖZBİLGİN, AHMET; Aykut, Gamze; Gursel, Ihsan; Gursel, Mayda (2022-11-01) Leishmania parasites harbor a unique network of circular DNA known as kinetoplast DNA (kDNA). The role of kDNA in leishmania infections is poorly understood. Herein, we show that kDNA delivery to the cytosol of Leishmania ...
Development and preclinical evaluation of virus-like particle vaccine against COVID-19 infection YILMAZ, İSMAİL CEM; et. al. (2021-09-01) Background Vaccines that incorporate multiple SARS-CoV-2 antigens can further broaden the breadth of virus-specific cellular and humoral immunity. This study describes the development and immunogenicity of SARS-CoV-2 VLP v...
Could Individuals From Countries Using BCG Vaccination Be Resistant to SARS-COV-2 Induced Infections? Ayanoğlu, İhsan Cihan; İpekoğlu, Emre Mert; Gürsel, Mayda (2020-01-01) The lower than expected number of SARS-CoV-2 cases in countries with fragile health systems is puzzling. Herein, we hypothesize that BCG vaccination policies and vaccine strain preferences adopted by different countries mi...

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