Ender Yıldırım

E-mail

yender@metu.edu.tr

Department

Department of Mechanical Engineering

ORCID

0000-0002-7969-2243

Scopus Author ID

36165070100

Web of Science Researcher ID

K-3962-2019

Rapid bacterial detection through microfluidic integration with a glucometer Eryilmaz, Merve; İLBASMIŞ TAMER, SİBEL; Panhwar, Sallahuddin; Tayyarcan, Emine Kübra; BOYACI, İSMAİL HAKKI; Suludere, Zekiye; ÇETİN, DEMET; Zengin, Adem; Yıldırım, Ender; TAMER, UĞUR (2025-08-01) We present a novel approach for sensitive and portable detection of pathogenic bacteria, which is crucial for household and clinical practice. Our method employs immunoliposomes, antibodies, and microchip to detect specifi...
ICU patient-on-a-chip emulating orchestration of mast cells and cerebral organoids in neuroinflammation Saglam-Metiner, Pelin; Yanasik, Sena; Odabasi, Yusuf Caglar; Modamio, Jennifer; Negwer, Moritz; Biray-Avci, Cigir; GÜLER, AYŞE; Erturk, Ali; Yıldırım, Ender; Yesil-Celiktas, Ozlem (2024-12-01) Propofol and midazolam are the current standard of care for prolonged sedation in Intensive Care Units (ICUs). However, the effects and mechanism of these sedatives in brain tissue are unclear. Herein, the development of a...
A microfluidic platform for real-time enumeration and high accuracy retrieval of a very low number of cells Şahin, Buket; Doğan, Begüm Şen; Özgür, Ebru; Zorlu, Özge; Yıldırım, Ender; Külah, Haluk (2024-10-01) In recent years, single cell isolation and analysis have become crucial, driven by the need to study rare cells in cell biology research, diagnostics, and personalized medicine. However, existing platforms for isolating sm...
Effect of Coating Formulations on Differentiation of Caco-2 Cells on Gut-On-a-Chip Platform Samanlı, Ezgi; Atik, Ali Can; Aslan, Zeynep Çağlayan; Aydın, Meltem Okan; Wyss, Hans; Dinçer, Can; Eberle , Wolfgang; Tekin, Hüseyin Cumhur; Külah, Haluk; Yıldırım, Ender (2024-07-03)
Levodopa and Dopamine Imprinted Polymeric Nanoparticles as a Recognition Layer in Gut-On-a-Chip Applications Targeting Parkinson’s Disease Aydın, Meltem Okan; Arslan, Zeynep Çağlayan; Atik, Ali Can; Salmanlı, Ezgi; Wyss, Hans; Can, Dinçer; Wolfgang, Eberle; Tekin, Hüseyin Cumhur; Külah, Haluk; Yıldırım, Ender (2024-07-03)
Modelling of villi differentiation in a gut-on-a-chip platform integrated with interdigitated TEER sensor Atik, Ali Can; Arslan, Zeynep Çağlayan; Aydın, Meltem Okan; Wyss, Hans; Dinçer, Can; Wolfgang, Eberle; Tekin, Hüseyin Cumhur; Külah, Haluk; Yıldırım, Ender (2024-06-03)
Utilization of cross-correlation function for assessment of replication quality in ultrasonic embossing of microchannels on polymethyl methacrylate Yıldırım, Ender; Ulku, Mert Kerem; Arıkan, Mehmet Ali Sahir (2024-01-01) Ultrasonic embossing—a process where a horn vibrating at 20–30 kHz compresses on a thermoplastic substrate sitting on a mold to replicate the features on the mold to the substrate—is a promising method for fabricating micr...
Humanized brain organoids-on-chip integrated with sensors for screening neuronal activity and neurotoxicity Saglam-Metiner, Pelin; Yıldırım, Ender; Dincer, Can; Basak, Onur; Yesil-Celiktas, Ozlem (2024-01-01) The complex structure and function of the human central nervous system that develops from the neural tube made in vitro modeling quite challenging until the discovery of brain organoids. Human-induced pluripotent stem cell...
Design of a microfluidic device for immunoaffinity-based isolation of circulating tumor cells with minimal clogging Sen-Dogan, Begum; Yıldırım, Ender; Sahin, Sebnem; Ozgur, Ebru; Zorlu, Ozge; Külah, Haluk (2023-12-01) Combining bioaffinity-based techniques with microfluidics is an effective strategy for the selective isolation of rare circulating tumor cells (CTCs) among peripheral blood cells. In this scope, designing a microfluidic ch...
Analytical Validation of a Spiral Microfluidic Chip with Hydrofoil-Shaped Pillars for the Enrichment of Circulating Tumor Cells Sen-Dogan, Begum; Demir, Mehmet Alper; Sahin, Buket; Yıldırım, Ender; Karayalcin, Gizem; Sahin, Sebnem; Mutlu, Ege; Toral, Taylan Berkin; Ozgur, Ebru; Zorlu, Ozge; Kulah, Haluk (2023-10-01) The isolation of circulating tumor cells (CTCs) from peripheral blood with high efficiency remains a challenge hindering the utilization of CTC enrichment methods in clinical practice. Here, we propose a microfluidic chann...

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