Osman Karaman

E-mail

karaman@metu.edu.tr

Department

Department of Chemistry

ORCID

0000-0002-8644-1063

Scopus Author ID

57204445132

Web of Science Researcher ID

ABA-2332-2020

Drastic Impact of Donor Substituents on Xanthenes in the PDT of Glioblastoma Karaman, Osman; Yesilcimen, E.; Forough, M.; Elmazoglu, Z.; Günbaş, Emrullah Görkem (2025-10-01) Even though significant progress has been made in treating various cancer types, brain cancers lag drastically. Several factors contribute, led by operational difficulties, the blood-brain barrier, and the tendency of recu...
Photodynamic Therapy against Glioblastoma: Investigating phenoselenazine based photosensitizer as a promising therapeutic agent Yeşilçimen, Elif; Karaman, Osman; Elmazoğlu, Zübeyir; Günbaş, Emrullah Görkem (2024-11-01) Objectives: Glioblastoma Multiforme (GBM) is themost aggressive malignant brain tumor. Photodynamictherapy (PDT) is a promising treatment strategyagainst GBM. It exerts cytotoxic effect by producingROS, mainly singlet oxyg...
NIR-ACTIVATED SILICON-RHODAMINE BASED PHOTOSENSITIZER AS A PROMISING THERAPEUTIC AGENT AGAINST GLIOBLASTOMA Özoğul, Naz; Karaman, Osman; Elmazoğlu, Zübeyir; Günbaş, Emrullah Görkem (2024-11-01) Objectives: Glioblastoma multiforme (GBM) remainsone of the most aggressive malignant tumors inthe central nervous system with low survival rate. Insufficientstandard care of the disease provoked needfor an alternative tre...
IODINATED SI-FLUORESCEIN BASED PHOTOSENSITIZER AS A THERANOSTIC AGENT AGAINST HUMAN GLIOBLASTOMA CELLS Kepil, Dilay; Karaman, Osman; Günbaş, Emrullah Görkem (2024-06-28) Introduction:Glioblastoma (GBM), which is a highly aggressive and lethal type of glioma, remains a significant challenge in modern medicine. Photodynamic therapy (PDT) is an emerging light-based alternative approach with...
β-Galactosidase Selective Si-Fluorescein Based Photosensitizer for Treatment of Brain Cancer Karaman, Osman; KEPİL, DİLAY; Günbaş, Emrullah Görkem (2024-03-07)
NIR ABSORBING PHENOSELENAZINE BASED PDT AGENTS TOWARDS EFFECTIVE TREATMENT OF TRIPLE NEGATIVE BREAST CANCER Karaman, Osman; Günbaş, Emrullah Görkem (2023-08-16) Cancer is still one of the leading health issues globally since effective treatment modalities for a range of cancer types are still elusive. Even with immense efforts in cancer research for diagnosis and treatment, vas...
Xanthene dyes for cancer imaging and treatment: A material odyssey Karaman, Osman; Alkan, Gizem Atakan; Kizilenis, Caglayan; Akgul, Cevahir Ceren; Gunbas, Gorkem (2023-01-01) Cancer is still among the leading health issues today, considering the cost, effectiveness, complexity ofdetection/treatment modalities and survival rates. One of the most important criteria for higher survivalrates is the...
Selenophene-Modified Boron Dipyrromethene-Based Photosensitizers Exhibit Photodynamic Inhibition on a Broad Range of Bacteria ÖZKETEN, AHMET ÇAĞLAR; Karaman, Osman; Ozdemir, Alara; Soysal, Isil; KIZILENİŞ, ÇAĞLAYAN; Chatzioglou, Aisegkioul Nteli; Çiçek, Yağız Arda; Kolemen, Safacan; Günbaş, Emrullah Görkem (2022-09-27) Microorganisms are crucial for human survival in view of both mutualistic and pathogen interactions. The control of the balance could be achieved by use of the antibiotics. There is a continuous arms race that exists betwe...
Superior Photodynamic Therapy of Colon Cancer Cells by Selenophene-BODIPY-Loaded Superparamagnetic Iron Oxide Nanoparticles Ozvural Sertcelik, Kubra Nur; Karaman, Osman; Almammadov, Toghrul; Günbaş, Emrullah Görkem; Kolemen, Safacan; Yagci Acar, Havva; Onbasli, Kubra (2022-01-01) © 2022 Wiley-VCH GmbH.Development of targeted nanoparticles as carriers to deliver photosensitizers to cancer cells is highly beneficial for ensuring the expected therapeutic outcome of photodynamic therapy. Herein, polyac...
Xanthene Dyes for Cancer Imaging and Treatment: A Material Odyssey Atakan, Gizem; Karaman, Osman; Alkan, Gizem Atakan; Kizilenis, Caglayan; Akgul, Cevahir Ceren; Gunbas, Gorkem (2022-01-01)

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