Nesrin Hasırcı

Center of Excellence in Biomaterials and Tissue Engineering
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Corrosion Resistance and Cytocompatibility of Magnesium-Calcium Alloys Modified with Zinc- or Gallium-Doped Calcium Phosphate Coatings
TAMAY, DİLARA GÖKSU; Gokyer, Seyda; Schmidt, Jurgen; Vladescu, Alina; HURİ, PINAR; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2022-01-12)
In orthopedic surgery, metals are preferred to support or treat damaged bones due to their high mechanical strength. However, the necessity for a second surgery for implant removal after healing creates problems. Therefore...
Enhancing esophageal repair with bioactive bilayer mesh containing FGF
Cesur, Ozkan; Endoğan Tanır, Tuğba; Celepli, Pinar; Ozarslan, Fatma; Hucumenoglu, Sema; KARAİBRAHİMOĞLU, Adnan; Hasırcı, Nesrin (2021-09-01)
We aimed to prepare a bioactive and biodegradable bilayer mesh formed by fibroblast growth factor (FGF) loaded gelatin film layer, and poly epsilon-caprolactone (PCL) film layer, and to investigate its treatment efficacy o...
Bioinks-materials used in printing cells in designed 3D forms
Tamay, Dilara Goksu; Hasırcı, Nesrin (2021-02-01)
Use of materials to activate non-functional or damaged organs and tissues goes back to early ages. The first materials used for this purpose were metals, and in time, novel materials such as ceramics, polymers and composit...
3D printed hybrid bone constructs of PCL and dental pulp stem cells loaded GelMA
Buyuksungur, Senem; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2021-01-01)
Fabrication of scaffolds using polymers and then cell seeding is a routine protocol of tissue engineering applications. Synthetic polymers have adequate mechanical properties to substitute for some bone tissue, but they ar...
Multifunctional periodontal membrane for treatment and regeneration purposes
Isik, Gulhan; Hasırcı, Nesrin; Tezcaner, Ayşen; Kızıltay, Aysel (2020-03-01)
Periodontitis is a chronic inflammatory disease that causes gum tissue degeneration and alveolar bone and tooth loss. The aim of this study is to develop a multifunctional matrix for the treatment of periodontitis and enha...
A two-compartment bone tumor model to investigate interactions between healthy and tumor cells
Komez, Aylin; Buyuksungur, Arda; Antmen Altunsoy, Ezgi; Swieszkowski, Wojciech; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2020-01-01)
We produced a novel three-dimensional (3D) bone tumor model (BTM) to study the interactions between healthy and tumor cells in a tumor microenvironment, the migration tendency of the tumor cells, and the efficacy of an ant...
Highly Crystalline Poly(L-lactic acid) Porous Films Prepared with CO2-philic, Hybrid, Liquid Cell Nucleators
Culhacioglu, Yagmur; Hasırcı, Nesrin; Dilek Hacıhabiboğlu, Çerağ (2019-12-18)
Supercritical CO2 (scCO(2)) foaming of poly(L-lactic acid) composite films with liquid polyhedral oligomeric silsesquioxanes (PLLA-POSS) was carried out to obtain polymer matrices for drug delivery applications. Highly cry...
Biomechanical analysis of a modified suture technique for septal extension grafts: Transloop suture
Gursoy, Koray; Teymur, Hakan; Kızıltay, Aysel; Hasırcı, Nesrin; Kocer, Ugur (2019-11-01)
Background: A successful rhinoplasty procedure requires a well-defined and properly projected nasal tip; however, surgical control of the nasal tip is difficult. The aim of this investigation was to assess the efficacy and...
Anatomical meniscus construct with zone specific biochemical composition and structural organization
Bahcecioglu, G.; Bilgen, B.; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2019-10-01)
A PCL/hydrogel construct that would mimic the structural organization, biochemistry and anatomy of meniscus was engineered. The compressive (380 +/- 40 kPa) and tensile modulus (18.2 +/- 0.9 MPa) of the PCL scaffolds were ...
3D and 4D Printing of Polymers for Tissue Engineering Applications
Tamay, Dilara Goksu; DURSUN USAL, TUĞBA; Alagoz, Ayse Selcen; Yucel, Deniz; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2019-07-09)
Three-dimensional (3D) and Four-dimensional (4D) printing emerged as the next generation of fabrication techniques, spanning across various research areas, such as engineering, chemistry, biology, computer science, and mat...
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