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Nesrin Hasırcı
E-mail
nhasirci@metu.edu.tr
Department
Center of Excellence in Biomaterials and Tissue Engineering
ORCID
0000-0002-4497-0194
Scopus Author ID
7003969314
Web of Science Researcher ID
I-4754-2018
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Variations of chemical, physical, mechanical properties, and biological and antimicrobial effectiveness of Ti alloys by coating with CaP doped with different amounts of Zn via micro-arc oxidation (MAO) technique
BÜYÜKSUNGUR, SENEM; Parau, Anca Constantina; Dinu, Mihaela; Pana, Iulian; Vitelaru, Catalin; Schmidt, Jürgen; Endoğan Tanır, Tuğba; Hasırcı, Vasıf Nejat; Vladescu (Dragomir), Alina; Hasırcı, Nesrin (2024-10-01)
Titanium alloys are preferred metals as implant materials due to their advantageous combination of low density and high biocompatibility. However, the augmentation of implant surfaces with calcium-based coatings becomes es...
MgCa-Based Alloys Modified with Zn- and Ga-Doped CaP Coatings Lead to Controlled Degradation and Enhanced Bone Formation in a Sheep Cranium Defect Model
Gokyer, Seyda; Monsef, Yanad Abou; BÜYÜKSUNGUR, SENEM; Schmidt, Jurgen; Vladescu Dragomir, Alina; Uygur, Sencer; Uygur, Sencer; ORHAN, KAAN; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin; Yilgor, Pinar (2024-01-01)
Mg-based biodegradable metallic implants are gaining increased attraction for applications in orthopedics and dentistry. However, their current applications are hampered by their high rate of corrosion, degradation, and ra...
Zn doped CaP coatings used for controlling the degradation rate of MgCa1 alloy: In vitro anticorrosive properties, sterilization and bacteria/cell-material interactions
Schmidt, Jürgen; Pana, Iulian; Bystrova, Anna; Dinu, Mihaela; Dekhtyar, Yuri; Vitelaru, Catalin; Gorohovs, Marks; Marinescu, Ioana Maria; HURİ, PINAR; Tamay, Dilara Goksu; Juravlea, Gabriela Andreea; Buyuksungur, Senem; Parau, Anca Constantina; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin; Vladescu, Alina (2023-02-01)
The purpose of this study was to investigate the effect of Zn doped CaP coatings prepared by micro-arc oxidation method, as a possible approach to control MgCa1 alloy degradation. All the prepared coatings comprised a calc...
Bioprinted scaffolds assembled as synthetic skin grafts by natural hydrogels containing fibroblasts and bioactive agents
Bostancı, Nazlı Seray; Büyüksungur, Senem; Hasırcı, Nesrin; Tezcaner, Ayşen (2023-01-01)
Hydrogel skin grafts provide a moist environment and act as a regenerative template to the newly formed tissue. In this study, we developed 3D-bio-printed hydrogels using methacrylated pectin and methacrylated gelatin toge...
Lithocholic acid conjugated mPEG-b-PCL micelles for pH responsive delivery to breast cancer cells
Isik, Gulhan; Kızıltay, Aysel; Hasırcı, Nesrin; Tezcaner, Ayşen (2022-06-10)
© 2022 Elsevier B.V.In this study, micelles composed of methoxy poly(ethylene glycol)-block-poly(ε-caprolactone) copolymer (mPEG-b-PCL), which has ionically conjugated lithocholic acid (LCA) and providing pH sensitive rele...
Potential of pectin for biomedical applications: a comprehensive review
Bostanci, Nazli Seray; Buyuksungur, Senem; Hasırcı, Nesrin; Tezcaner, Ayşen (2022-06-01)
Pectin is a polysaccharide extracted from various plants, such as apples, oranges, lemons, and it possesses some beneficial effects on human health, including being hypoglycemic and hypocholesterolemic. Therefore, pectin i...
Coating of silver nanoparticles on polyurethane film surface by green chemistry approach and investigation of antibacterial activity against S. epidermidis
Kara, Filiz; AKSOY, EDA AYŞE; Aksoy, Serpil; Hasırcı, Nesrin (2022-05-01)
© The Author(s) 2022.Silver nanoparticles with potential antibacterial properties are included in biomaterials for the production of medical devices, which are used for diagnoses or treatment purposes. The aim of the curre...
Corrosion Resistance and Cytocompatibility of Magnesium-Calcium Alloys Modified with Zinc- or Gallium-Doped Calcium Phosphate Coatings
TAMAY, DİLARA GÖKSU; Gokyer, Seyda; Schmidt, Jurgen; Vladescu, Alina; HURİ, PINAR; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2022-01-12)
In orthopedic surgery, metals are preferred to support or treat damaged bones due to their high mechanical strength. However, the necessity for a second surgery for implant removal after healing creates problems. Therefore...
pH responsive release of curcumin from photocrosslinked pectin/gelatin hydrogel wound dressings
Bostancı, Nazlı Seray; Büyüksungur, Senem; Hasırcı, Nesrin; Tezcaner, Ayşen (2022-01-01)
© 2022 Elsevier B.V.The aim of this study was to develop hydrogel wound dressings made of photocrosslinkable pectin and gelatin with pH dependent release of curcumin, an antimicrobial agent. Methacrylated forms of pectin a...
Biocompatible coatings for implants Biokompatible Beschichtungen für Implantate
Schmidt, Jürgen; Vladescu, Alina; Hasırcı, Nesrin (2022-01-01)
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