Nesrin Hasırcı

E-mail
nhasirci@metu.edu.tr
Department
Center of Excellence in Biomaterials and Tissue Engineering
Scopus Author ID
Web of Science Researcher ID
Lithocholic acid conjugated mPEG-b-PCL micelles for pH responsive delivery to breast cancer cells
Isik, Gulhan; Kızıltay, Aysel; Hasırcı, Nesrin; Tezcaner, Ayşen (2022-06-10)
© 2022 Elsevier B.V.In this study, micelles composed of methoxy poly(ethylene glycol)-block-poly(ε-caprolactone) copolymer (mPEG-b-PCL), which has ionically conjugated lithocholic acid (LCA) and providing pH sensitive rele...
Potential of pectin for biomedical applications: a comprehensive review
Bostanci, Nazli Seray; Buyuksungur, Senem; Hasırcı, Nesrin; Tezcaner, Ayşen (2022-06-01)
Pectin is a polysaccharide extracted from various plants, such as apples, oranges, lemons, and it possesses some beneficial effects on human health, including being hypoglycemic and hypocholesterolemic. Therefore, pectin i...
Coating of silver nanoparticles on polyurethane film surface by green chemistry approach and investigation of antibacterial activity against S. epidermidis
Kara, Filiz; AKSOY, EDA AYŞE; Aksoy, Serpil; Hasırcı, Nesrin (2022-05-01)
© The Author(s) 2022.Silver nanoparticles with potential antibacterial properties are included in biomaterials for the production of medical devices, which are used for diagnoses or treatment purposes. The aim of the curre...
Corrosion Resistance and Cytocompatibility of Magnesium-Calcium Alloys Modified with Zinc- or Gallium-Doped Calcium Phosphate Coatings
TAMAY, DİLARA GÖKSU; Gokyer, Seyda; Schmidt, Jurgen; Vladescu, Alina; HURİ, PINAR; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2022-01-12)
In orthopedic surgery, metals are preferred to support or treat damaged bones due to their high mechanical strength. However, the necessity for a second surgery for implant removal after healing creates problems. Therefore...
pH responsive release of curcumin from photocrosslinked pectin/gelatin hydrogel wound dressings
Bostancı, Nazlı Seray; Büyüksungur, Senem; Hasırcı, Nesrin; Tezcaner, Ayşen (2022-01-01)
© 2022 Elsevier B.V.The aim of this study was to develop hydrogel wound dressings made of photocrosslinkable pectin and gelatin with pH dependent release of curcumin, an antimicrobial agent. Methacrylated forms of pectin a...
Enhancing esophageal repair with bioactive bilayer mesh containing FGF
Cesur, Ozkan; Endoğan Tanır, Tuğba; Celepli, Pinar; Ozarslan, Fatma; Hucumenoglu, Sema; KARAİBRAHİMOĞLU, Adnan; Hasırcı, Nesrin (2021-09-01)
We aimed to prepare a bioactive and biodegradable bilayer mesh formed by fibroblast growth factor (FGF) loaded gelatin film layer, and poly epsilon-caprolactone (PCL) film layer, and to investigate its treatment efficacy o...
Bioinks-materials used in printing cells in designed 3D forms
Tamay, Dilara Goksu; Hasırcı, Nesrin (2021-02-01)
Use of materials to activate non-functional or damaged organs and tissues goes back to early ages. The first materials used for this purpose were metals, and in time, novel materials such as ceramics, polymers and composit...
3D printed hybrid bone constructs of PCL and dental pulp stem cells loaded GelMA
Buyuksungur, Senem; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2021-01-01)
Fabrication of scaffolds using polymers and then cell seeding is a routine protocol of tissue engineering applications. Synthetic polymers have adequate mechanical properties to substitute for some bone tissue, but they ar...
Multifunctional periodontal membrane for treatment and regeneration purposes
Isik, Gulhan; Hasırcı, Nesrin; Tezcaner, Ayşen; Kızıltay, Aysel (2020-03-01)
Periodontitis is a chronic inflammatory disease that causes gum tissue degeneration and alveolar bone and tooth loss. The aim of this study is to develop a multifunctional matrix for the treatment of periodontitis and enha...
A two-compartment bone tumor model to investigate interactions between healthy and tumor cells
Komez, Aylin; Buyuksungur, Arda; Antmen Altunsoy, Ezgi; Swieszkowski, Wojciech; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2020-01-01)
We produced a novel three-dimensional (3D) bone tumor model (BTM) to study the interactions between healthy and tumor cells in a tumor microenvironment, the migration tendency of the tumor cells, and the efficacy of an ant...
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