Deniz Cansen Kahraman

E-mail

cansen@metu.edu.tr

Department

Graduate School of Informatics

ORCID

0000-0002-3381-5463

SAT-163 Inflammation-associated gene expression profiles distinguishing significant fibrosis in metabolic dysfunction-associated steatotic liver disease (MASLD): evidence from a Turkish patient cohort Kahraman, Deniz Cansen; Sinoplu, Esra; Turan Gökçe, Dilara; Kiremitci, Saba; İdilman, Ramazan (2026-05-27)
Unveiling Molecular Biomarkers of MASLD Fibrosis: A Transcriptomic and Pathway Enrichment Analysis Nalbat, Esra; Kahraman, Deniz Cansen (2025-02-15)
Target-specific de novo design of drug candidate molecules with graph-transformer-based generative adversarial networks Ünlü, Atabey; Çevrim, Elif; Yiğit, Melih Gökay; Sarıgün, Ahmet; Çelikbilek, Hayriye; Bayram, Osman; Kahraman, Deniz Cansen; OLĞAÇ, ABDURRAHMAN; Rifaioglu, Ahmet Sureyya; BANOĞLU, ERDEN; Doğan, Tunca (2025-01-01) Discovering novel drug candidate molecules is a fundamental step in drug development. Generative deep learning models can sample new molecular structures from learned probability distributions; however, their practical use...
Deciphering Transcriptional Landscapes of Mild and Advanced MASLD Fibrosis: Insights into Differential Gene Expression, Pathway Enrichment, and Drug Repurposing Opportunities Nalbat, Esra; Kahraman, Deniz Cansen (2024-12-20)
Design, synthesis, and evaluation of novel Indole-Based small molecules as sirtuin inhibitors with anticancer activities. Binarci, Busra; Kilic, Ensar Korkut; Dogan, Tunca; Cetin Atalay, Rengul; Kahraman, Deniz Cansen; Nacak Baytas, Sultan (2024-11-01) Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide, driven mainly by chronic hepatitis infections and metabolic disorders, which highlights the urgent need for novel therapeutic strateg...
Targeting sirtuins with novel indole derivatives: implications for anticancer activity in hepatocellular carcinoma Bınarcı, Büşra; DOĞAN, TUNCA; ATALAY, RENGÜL; Kahraman, Deniz Cansen; BAYTAŞ, SULTAN (2024-02-22)
Exploring early markers of fibrosis progression in metabolic dysfunction–associated steatotic liver disease in Turkiye Kahraman, Deniz Cansen; Sinoplu, Esra; ATALAY, RENGÜL; İDİLMAN, RAMAZAN (2024-02-17)
Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors Hawash, Mohammed; Jaradat, Nidal; Abualhasan, Murad; ŞÜKÜROĞLU, MURAT KADİR; Qaoud, Mohammed T.; Kahraman, Deniz Cansen; Daraghmeh, Heba; Maslamani, Leen; Sawafta, Mais; Ratrout, Ala; Issa, Linda (2023-12-01) Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. Objectives: This study aimed to design and synthesize a novel series of ...
Repurposing Drugs to Target Molecular Networks in Hepatocellular Carcinoma Cells & Stem Cells for Innovative Treatment Strategies Sinoplu, Esra; TUNÇBAĞ, NURCAN; Kahraman, Deniz Cansen; ATALAY, RENGÜL (2023-12-01)
DeepResponse: Large Scale Prediction of Cancer Cell Line Drug Response with Deep Learning Based Pharmacogenomic Modelling Kahraman, Deniz Cansen; DOĞAN, TUNCA (2023-10-04)

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