Murat Erdem

E-mail

merdem@metu.edu.tr

Department

Department of Biology

ORCID

0000-0002-6291-0320

Scopus Author ID

55988030000

Web of Science Researcher ID

ABA-1283-2020

Clinical Validation and Evaluation of a Colorimetric SARS-CoV-2 RT-LAMP Assay Against RT-PCR Erdem, Murat; Andac, Ayse; Özketen, Ahmet Çağlar; Karahan, Gizem; Tozluyurt, Abdullah; Palaz, Fahreddin; ALP, ALPASLAN; ÜNAL, Serhat (2023-06-23) Objective: Reverse transcriptase loop-mediated isothermal amplification (RT-LAMP) is one of the time-saving, accurate, and cost-effective alternative methods to real-time polymer- ase chain reaction (RT-PCR). This study ai...
Thiophene BODIPY-substituted cyclotriphosphazene-derived photosensitizers for photodynamic therapy applications YILDIZ GÜL, Elif; Erdem, Murat; Kazan, Hasan Hüseyin; TANRIVERDİ EÇİK, Esra (2023-01-01) Cancer is one of the most important health problems that people are facing today. Photodynamic therapy (PDT) is regarded as a promising approach for cancer treatment based on the interaction of a photosensitizer and laser ...
HNRNPA1 Isoform Switch in Breast Cancers Erson Bensan, Ayşe Elif; Özgül, İbrahim; Erdem, Murat; Döken, Didem Naz (2021-11-01) Roles of HNRNPA1 are beginning to emerge in cancers; however, mechanisms causing deregulation of HNRNPA1 function remain elusive. Here, we identify and characterize an isoform switch between the 3’-UTR isoforms of HNRNPA1....
HNRNPA1 (Heterogeneous nuclear ribonucleoprotein A1) Özgül, İbrahim; Erdem, Murat; Erson Bensan, Ayşe Elif (2019-01-01) Heterogeneous nuclear ribonucleoprotein (HNRNPA1) gene maps to chromosome 12, plus strand and has 13 exons and 12 introns. There are three reported transcripts due to the alternative splicing. HNRNPA1 is one of the most ab...
Folic acid-conjugated polyethylene glycol-coated magnetic nanoparticles for doxorubicin delivery in cancer chemotherapy: Preparation, characterization and cytotoxicity on HeLa cell line Erdem, Murat; Gündüz, Ufuk (2017-08-01) Conventional chemotherapy is the most valid method to cope with cancer; however, it has serious drawbacks such as decrease in production of blood cells or inflammation of the lining of the digestive tract. These side effec...
APA isoform diversity in triple negative breast cancers AKMAN TUNCER, HESNA BEGÜM; ÖYKEN, MERVE; AĞUŞ, HIZLAN HINCAL; Erdem, Murat; Çiçek, Esra; Can, Tolga; Erson Bensan, Ayşe Elif (2017-04-05) Alternative polyadenylation (APA) plays a role in gene expression regulation generally by shortening of 3'UTRs and relieving microRNA-mediated repression. Therefore, APA is gaining increased attention as a potential mechan...
Analyses of Changes in Dielectric Properties of Doxorubicin Resistant Breast Cancer Cells Through Electrorotation With 3D Electrodes Bahrieh, Garsha; Erdem, Murat; Özgür, Ebru; Gündüz, Ufuk; Külah, Haluk (null; 2016-07-16)
LABEL-FREE DETECTION OF LEUKEMIA CELLS WITH A LAB-ON-A-CHIP SYSTEM INTEGRATING DIELECTROPHORESIS AND CMOS IMAGING Demircan, Y.; Orguc, S.; Musayev, J.; Ozgur, E.; Erdem, Murat; Gündüz, Ufuk; Eminoglu, S.; Külah, Haluk; Akın, Tayfun (2015-06-25) This paper presents a fully-integrated lab-on-a-chip (LOC) system for label-free detection and real-time counting of dielectrophoretically trapped multidrug resistant (MDR) K562 cells. The system integrates a parylene-base...
DETERMINATION OF MULTIDRUG RESISTANCE LEVEL IN K562 LEUKEMIA CELLS BY 3D-ELECTRODE CONTACTLESS DIELECTROPHORESIS Demircan, Y.; Erdem, Murat; Ozgur, E.; Gündüz, Ufuk; Külah, Haluk (2014-01-30) In this study, 3D-electrode contactless dielectrophoresis (DEP) system is utilized to drive a relationship between the drug resistance level and dielectrophoretic response of doxorubicin resistant K562 (K562/dox) cells. Th...
Assessment of effects of multi drug resistance on dielectric properties of K562 leukemic cells using electrorotation Bahrieh, Garsha; Erdem, Murat; Ozgur, Ebru; Gündüz, Ufuk; Külah, Haluk (2014-01-01) In this study, dielectric characterization of multidrug resistant (MDR) K562 human leukemia cells was carried out using a MEMS based electrorotation (ER) device with 3D electrodes. P-glycoprotein (P-gp) dependent MDR cause...

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