How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?

Date

2009-09-01

Author

Karahan, Mehmet Ali
Kulacoglu, Hakan
Seker, Duray
Ergul, Zafer
Kızıltay, Aysel
Yilmazer, Demet
Captug, Ozge
Yavuz, Alper
Serbetci, Kemal
BİLGİLİ, HASAN
Hasırcı, Nesrin

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Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histopathological examination, the only difference noted was in the vascularization scores of normally fed rats. For malnourished subjects that survived after surgery, the use of polypropylene mesh appeared safe in the closure of abdominal-wall defects, with no increase in infection rate and satisfactory wound healing.

Subject Keywords

Malnutrition, Tensile strength, Wound healing, Mesh, Hernia repair

URI

https://hdl.handle.net/11511/31078

Journal

CENTRAL EUROPEAN JOURNAL OF MEDICINE

DOI

https://doi.org/10.2478/s11536-009-0029-2

Collections

Graduate School of Natural and Applied Sciences, Article

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Citation Formats

M. A. Karahan et al., “How safe is the use of prosthetic materials in the repair of abdominal-wall defects in malnourished subjects?,” CENTRAL EUROPEAN JOURNAL OF MEDICINE, pp. 331–336, 2009, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/31078.