New phosphine oxide aziridinyl phosphonates as chiral Lewis bases for the Abramov-type phosphonylation of aldehydes

Date

2013-05-31

Author

Doğan, Özdemir
Isci, Muhammet
Aygun, Muhittin

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A series of Lewis bases were screened for Abramov-type phosphine additions to aldehydes. A novel phosphine oxide aziridinyl phosphonate POAP-A was found to be better than the others in forming the product in 96% yield and with 42% ee. The absolute configuration of the newly synthesized POAP Lewis bases was determined by single-crystal X-ray analysis.

Subject Keywords

Physical and Theoretical Chemistry, Inorganic Chemistry, Organic Chemistry, Catalysis

URI

https://hdl.handle.net/11511/35355

Journal

TETRAHEDRON-ASYMMETRY

DOI

https://doi.org/10.1016/j.tetasy.2013.04.005

Collections

Department of Chemistry, Article

Citation Formats

Ö. Doğan, M. Isci, and M. Aygun, “New phosphine oxide aziridinyl phosphonates as chiral Lewis bases for the Abramov-type phosphonylation of aldehydes,” TETRAHEDRON-ASYMMETRY, vol. 24, pp. 562–567, 2013, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/35355.