New phosphine oxide aziridinyl phosphonates as chiral Lewis bases for the Abramov-type phosphonylation of aldehydes

2013-05-31
Doğan, Özdemir
Isci, Muhammet
Aygun, Muhittin
A series of Lewis bases were screened for Abramov-type phosphine additions to aldehydes. A novel phosphine oxide aziridinyl phosphonate POAP-A was found to be better than the others in forming the product in 96% yield and with 42% ee. The absolute configuration of the newly synthesized POAP Lewis bases was determined by single-crystal X-ray analysis.

Citation Formats
Ö. Doğan, M. Isci, and M. Aygun, “New phosphine oxide aziridinyl phosphonates as chiral Lewis bases for the Abramov-type phosphonylation of aldehydes,” TETRAHEDRON-ASYMMETRY, vol. 24, pp. 562–567, 2013, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/35355.