Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
Submicromolar, selective G-quadruplex ligands from one pot: Thermodynamic and structural studies of human telomeric DNA binding by azacyanines
Date
2008-08-11
Author
Persil Çetinkol, Özgül
Nanjunda, Rupesh K.
Wilson, W. David
HUD, Nicholas V.
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
33
views
0
downloads
Cite This
Subject Keywords
Organic Chemistry
,
Molecular Medicine
,
Biochemistry
,
Molecular Biology
URI
https://hdl.handle.net/11511/37317
Journal
CHEMBIOCHEM
DOI
https://doi.org/10.1002/cbic.200800234
Collections
Department of Chemistry, Article
Suggestions
OpenMETU
Core
Chemoselective Immobilization of Proteins by Microcontact Printing and Bio-orthogonal Click Reactions
Tolstyka, Zachary P.; Richardson, Wade; Bat, Erhan; Stevens, Caitlin J.; Parra, Dayanara P.; Dozier, Jonathan K.; Distefano, Mark D.; Dunn, Bruce; Maynard, Heather D. (Wiley, 2013-12-16)
Herein, a combination of microcontact printing of functionalized alkanethiols and site-specific modification of proteins is utilized to chemoselectively immobilize proteins onto gold surfaces, either by oxime- or copper-catalyzed alkyne-azide click chemistry. Two molecules capable of click reactions were synthesized, an aminooxy-functionalized alkanethiol and an azide-functionalized alkanethiol, and self-assembled monolayer (SAM) formation on gold was confirmed by IR spectroscopy. The alkanethiols were then...
DNA Walker-Regulated Cancer Cell Growth Inhibition
Li, Feiran; Cha, Tae-Gon; Pan, Jing; Özçelikkale, Altuğ; Han, Bumsoo; Choi, Jong Hyun (Wiley, 2016-06-01)
We demonstrate a DNAzyme-based walker system as a controlled oligonucleotide drug AS1411 release platform for breast cancer treatment. In this system, AS1411 strands are released from fuel strands as a walker moves along its carbon nanotube track. The release rate and amount of anticancer oligonucleotides are controlled by the walker operation. With a walker system embedded within the collagen extracellular matrix, we show that this drug release system can be used for in situ cancer cell growth inhibition.
Alpha crystallin domain mutations increase holdase capacity of the archeal small heat shock protein, Tpv HSP 14.3
Kocabıyık, Semra (2016-07-25)
Protein stability involves the ability of native, folded protein structure to withstand the disruptive, denaturing effects of the external environment. Proteins used in many medical or biotechnological processes are often subjected to conditions which may trigger their degradation, aggregation or inactivation. Therefore, stabilization of proteins is one of the most challenging tasks that has to be addressed in protein based technologies. Many methods have been proposed for improvement of chemical and/or phy...
Phanerochaete chrysosporium soluble proteome as a prelude for the analysis of heavy metal stress response
Ozcan, Servet; Yildirim, Volkan; Kaya, Levent; Albrecht, Dirk; Becher, Doerte; Hecker, Michael; Özcengiz, Gülay (Wiley, 2007-04-01)
A 2-D reference map in pI range 3-10 was constructed for the soluble protein fraction of Phancrochaete chrysosporium growing vegetatively under standard conditions. Functional annotation could be made for 517 spots out of 720 that were subjected to MALDI-TOF-MS analysis, according to the specific accession numbers from the P. chrysosporium genomic database. Further analysis of the data revealed 314 distinct ORFs, 118 of which yielded multiple spots on the master gel. Functional classification of the protein...
Post-translational modification of vascular endothelial growth factor (VEGF) in colon cancer cells
Tuncer, S.; Solel, E.; Banerjee, Sreeparna (2016-09-01)
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
Ö. Persil Çetinkol, R. K. Nanjunda, W. D. Wilson, and N. V. HUD, “Submicromolar, selective G-quadruplex ligands from one pot: Thermodynamic and structural studies of human telomeric DNA binding by azacyanines,”
CHEMBIOCHEM
, pp. 1889–1892, 2008, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/37317.