Show/Hide Menu
Hide/Show Apps
Logout
Türkçe
Türkçe
Search
Search
Login
Login
OpenMETU
OpenMETU
About
About
Open Science Policy
Open Science Policy
Communities & Collections
Communities & Collections
Help
Help
Frequently Asked Questions
Frequently Asked Questions
Guides
Guides
Thesis submission
Thesis submission
MS without thesis term project submission
MS without thesis term project submission
Publication submission with DOI
Publication submission with DOI
Publication submission
Publication submission
Supporting Information
Supporting Information
General Information
General Information
Copyright, Embargo and License
Copyright, Embargo and License
Contact us
Contact us
Sheep tissue acetyl coenzyme A-dependent arylamine N-acetyltransferases
Date
1997-11-01
Author
Güray, Nülüfer Tülün
Metadata
Show full item record
This work is licensed under a
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
.
Item Usage Stats
35
views
0
downloads
Cite This
Acetyl coenzyme A-dependent arylamine N-acetyltransferases (NATs), EC 2.3.1.5. were measured in sheep tissues (N = 14) using p-aminobenzoic acid (PABA) as a substrate. Specific activities of liver, kidney, and lung NATs were 5.3 X 10(-3) +/- 1.4 (mean +/- SE) nmoles.min(-1).mg protein(-1), 3.4 X 10(-3) +/- 1.1 nmoles.min(-1).mg protein(-1), 2.5 X 10(-3) +/- 1.2 nmoles.min(-1).mg protein(-1), respectively. K-m values were 53 +/- 3 mu M for liver, 34 +/- 2 mu M for kidney, and 28 +/- 2 mu M for lung tissue. Optimum pH for the acetylation reaction was found as 7.5. The enzyme activity was stable for at least 6 months in all tissues, when stored at -70 degrees C. The enzyme from sheep tissues were quite heat stable. Inhibition studies showed that N-ethylmaleimide was a potent inhibitor of sheep tissue NAT enzymes. (C) 1997 Elsevier Science Inc.
Subject Keywords
AcCoA-dependent N-acetyltransferase
,
N-acetylation
,
N-acetyltransferases
,
Sheep tissue
URI
https://hdl.handle.net/11511/39789
Journal
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
DOI
https://doi.org/10.1016/s0742-8413(97)00175-8
Collections
Department of Biology, Article
Suggestions
OpenMETU
Core
Electrochemical polymerization of para-substituted haloanilines
Cihaner, A; Önal, Ahmet Muhtar (Informa UK Limited, 2006-01-01)
Polyhaloanilines: poly(4-fluoroaniline) (P4FAN), poly(4-chloroaniline) (P4CAN), and poly(4-bromoaniline) (P4BAN), are synthesized from para-substituted haloaniline monomers; 4-fluoroaniline (4FAN), 4-chloroaniline (4CAN), and 4-bromoaniline (4BAN), respectively, via constant potential electrolysis (CPE) in acetonitrile-water mixture (1:1 v/v) with NaClO4 as supporting electrolyte. Prior to CPE, electrochemical behavior of the monomers were investigated in organic medium utilizing cyclic voltammetry (CV). Th...
SYNTHESIS AND CHARACTERIZATION OF POLY(DICHLOROPHENYLENE OXIDE)S BASED ON THE ELECTROOXIDATION OF BIS(2,4,6-TRICHLOROPHENOXO)BIS(PYRIDINE)COPPER(II) COMPLEX
SEN, S; KISAKUREK, D (Elsevier BV, 1993-01-01)
Electroinitiated polymerization of bis(2,4,6-trichlorophenoxo)bis(pyridine)copper(II) complex was achieved in dimethylformamide by constant potential electrolysis under air and N2. The polymers obtained at several potentials were characterized by H-1 n.m.r., C-13 n.m.r., FTi.r. and d.s.c., and were found to be branched. The kinetics of the polymerization were followed by in situ cyclic voltammetry measurements at 13.5 and 20-degrees-C during electrolysis. As found for the thermal polymerization of this comp...
ASYMMETRİC ORGANOCATALYTİC SULFA -MİCHAEL REACTİONS OF THİOLS WİTH a,b -UNSATURATED NİTRİLES TİYOLLERİN a,b -DOYMAMIŞ NİTRİLLERLE ASİMETRİK ORGANOKATALİTİK SULFA-MİCHAEL TEPKİMELERİ
Tanyeli, Cihangir(2017-12-31)
ASYMMETRİC ORGANOCATALYTİC SULFA -MİCHAEL REACTİONS OF THİOLS WİTH a,b -UNSATURATED NİTRİLES TİYOLLERİN a,b -DOYMAMIŞ NİTRİLLERLE ASİMETRİK ORGANOKATALİTİK SULFA-MİCHAEL TEPKİMELERİ
FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ
Dilek Hacıhabiboğlu, Çerağ(2014-12-31)
POLYHEDRAL OLİGOMERİC SİLSESQUİOXANE (POSS) SOLUBİLİTİES SUPERCRİTİCAL CARBON DİOXİDE
Boron trifluoride mediated addition of nucleophiles to endo- and exo-substituted norbornene derivatives
İŞLEYEN, Alper; SAYRAÇ, Tuğmaç; Doğan, Özdemir (2004-01-01)
Remote substituent effects on the regioselectivity and stereoselectivity in the boron trifluoride mediated addition of nucleophiles (iodide and bromide) to endo- and exo-2-substituted norbornene derivatives have been investigated. The main products of the reactions resulted from the regioselective addition of nucleophiles to the double bond of norbornene derivatives. Products resulting from the Wagner-Meerwein type rearrangement were also isolated in considerable amounts. All of the reactions gave the addit...
Citation Formats
IEEE
ACM
APA
CHICAGO
MLA
BibTeX
N. T. Güray, “Sheep tissue acetyl coenzyme A-dependent arylamine N-acetyltransferases,”
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
, pp. 305–310, 1997, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/39789.