Ancient Mitochondrial Genomes Reveal the Absence of Maternal Kinship in the Burials of catalhoyuk People and Their Genetic Affinities

Chylenski, Maciej
Ehler, Edvard
Somel, Mehmet
Yaka, Reyhan
Krzewinska, Maja
Dabert, Miroslawa
Juras, Anna
Marciniak, Arkadiusz
catalhoyuk is one of the most widely recognized and extensively researched Neolithic settlements. The site has been used to discuss a wide range of aspects associated with the spread of the Neolithic lifestyle and the social organization of Neolithic societies. Here, we address both topics using newly generated mitochondrial genomes, obtained by direct sequencing and capture-based enrichment of genomic libraries, for a group of individuals buried under a cluster of neighboring houses from the classical layer of the site's occupation. Our data suggests a lack of maternal kinship between individuals interred under the floors of catalhoyuk buildings. The findings could potentially be explained either by a high variability of maternal lineages within a larger kin group, or alternatively, an intentional selection of individuals for burial based on factors other than biological kinship. Our population analyses shows that Neolithic Central Anatolian groups, including catalhoyuk, share the closest affinity with the population from the Marmara Region and are, in contrast, set further apart from the Levantine populations. Our findings support the hypothesis about the emergence and the direction of spread of the Neolithic within Anatolian Peninsula and beyond, emphasizing a significant role of Central Anatolia in this process.


Morphometric, mtdna and microsatellite analysis in honeybee populations (apis mellifera L.) of north and northwest İran
Farhoud, Houman Jabbari; Kence, Meral; Department of Biotechnology (2004)
Morphometric measurements, mitochondrial DNA analyses and 5 microsatellite loci were used to investigate variation in the honeybee populations of Iran and comparing it with the Turkish populations. Five honeybee populations were sampled from North and west north of Iran. In morphometric aspect of the study 23 characters were measured from left forewings and hindlegs of honey bee samples. The data were analysed by multivariate statistical analyses. By using mtDNA analyses length polymorphism of the intergeni...
Genetic diversity of native and crossbreed sheep breeds in Anatolia
Koban, Evren; Togan, İnci Zehra; Department of Biology (2004)
In this study the genetic diversity in Turkish native sheep breeds was investigated based on microsatellite DNA loci. In total, 423 samples from 11 native and crossbreed Turkish sheep breeds (Akkaraman, Morkaraman, Kivircik, Ivesi, Dagliç, Karayaka, Hemsin, Norduz, Kangal, Konya Merinosu, Türkgeldi) and one Iraqi breed (Hamdani) were analyzed by sampling from breeding farms and local breeders. After excluding close relatives by Kinship analysis, the genetic variation within breeds was estimated as gene dive...
Identification and analysis of genomic regions with large between-population differentiation in humans
Myles, S.; Tang, K.; Somel, Mehmet; Green, R. E.; Kelso, J.; Stoneking, M. (Wiley, 2008-01-01)
The primary aim of genetic association and linkage studies is to identify genetic variants that contribute to phenotypic variation within human populations. Since the overwhelming majority of human genetic variation is found within populations, these methods are expected to be effective and can likely be extrapolated from one human population to another. However, they may lack power in detecting the genetic variants that contribute to phenotypes that differ greatly between human populations. Phenotypes that...
Evaluation of salt tolerance in sto transformed Arabidopsis thaliana and Nicotiana tabacum plants
Selçuk, Feyza; Yücel, Ayşe Meral; Department of Biology (2004)
Salinity is one of the limiting factors of crop development. Together with causing water loss from plant tissues, salinity also leads to ion toxicity. Under salt stress, increase in Ca+2 concentration in cytosol can decrease the deleterious effects of stress. The binding of Ca+2 to calmodulin initiates a signaling cascade involving the activation of certain transcription factors like STO and STZ. This signal transduction pathway regulates transport of proteins that control net Na+ influx across the plasma m...
The phylogenetic analysis of pinus nigra arnold subspecies pallasiana varieties with respect to non-coding trn regions of chloroplast genome
Güvendiren Gülsoy, Aysun Demet; Kaya, Zeki; Department of Biology (2009)
More than half of the Pinaceae is including in genus Pinus covers the large parts of vegetation of northern hemisphere. The Anatolian Black Pine is one of the subspecies of European Black Pine, growing naturally as a widespread mid elevation species of Taurus, western Anatolian and northern Anatolian Mountains of Turkey. Although it is disputed that there are 5 varieties of Anatolian black pine but three of these are well recognized. These are Pinus nigra subsp. pallasiana var. pallasiana, Pinus nigra Arnol...
Citation Formats
M. Chylenski et al., “Ancient Mitochondrial Genomes Reveal the Absence of Maternal Kinship in the Burials of catalhoyuk People and Their Genetic Affinities,” GENES, pp. 0–0, 2019, Accessed: 00, 2020. [Online]. Available: