Functional regeneration of glossopharyngeal nerve through micromachined sieve electrode arrays

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1992-10-23

Author

Bradley, Robert M.
Smoke, Richard H.
Akın, Tayfun
Najafi, Khalil

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To assess the potential of micromachined silicon sieve electrodes for long term recordings from single afferent sensory fibers, we implanted them between the cut ends of rat glossopharyngeal nerves which innervate taste and somatosensory receptors on the posterior tongue. After the implants had been in place for an average of 101 days nerve regeneration was measured using histological and electrophysiological methods. Axons of the glossopharyngeal nerve regenerated through holes in the sieves and supported the functional regeneration of taste, thermal and mechanoreceptors.

Subject Keywords

Developmental Biology, General Neuroscience, Molecular Biology, Clinical Neurology

URI

https://hdl.handle.net/11511/41978

Journal

Brain Research

DOI

https://doi.org/10.1016/0006-8993(92)91031-9

Collections

Department of Electrical and Electronics Engineering, Article

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Citation Formats

R. M. Bradley, R. H. Smoke, T. Akın, and K. Najafi, “Functional regeneration of glossopharyngeal nerve through micromachined sieve electrode arrays,” Brain Research, pp. 84–90, 1992, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/41978.