Numerical analysis of spinal cord stimulation with triple leads with guarded cathode

Date

2015-11-06

Author

Durlu, Caglayan
Zengin, Reyhan
Gençer, Nevzat Güneri
Kucukdeveci, Fikret

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

105
views

0
downloads

Spinal cord stimulation (SCS) is a alternative treatment method for drug free treatment for chronic pain. Electrodes are placed to Spinal column's epidural tissue to blocked transfer of pain to brain and to stimulate dorsally column of pain. Today there are two two designs of electrode which are used in Spinal cord stimulation (SCS): a percutaneous (PERC) design, consisting of annular electrodes distributed along a flexible cylindrical shaft, which is inserted with a hypodermic needle; and a laminectomy/paddle design (LAM) implanted during a surgical laminectomy, consisting of a grid of rectangular electrodes on a flexible planar substrate. Also, only controlled percutaneous cathode electrode is used for stimulation a certain area in spinal cord. In this study, numerical studies of direct current application are done using percutaneous lead with 3-electrode model. Spinal canal is modeled in four layers which are epidural fat, CSF, white matter and gray matter tissues as 3D with using Finite Element Method (FEM). The lead with 3-electrode is placed in epidural fat. Anode and cathode electrodes are stimulated so as to flow current respectively 0.25mA and -2mA. At the contact surface of electrodes and epidural fat, obtained maximum current density is 128.161 mA/cm(2) and this value is in the safety limits. The maximum electrical voltage occurred in the spinal canal is 2.133 V and this value is in the interval of perception value for patients.

Subject Keywords

Electrical stimulation, Pain, Numerical analysis, Cathodes, Spinal cord, Lead

URI

https://hdl.handle.net/11511/46880

DOI

https://doi.org/10.1109/biyomut.2015.7369456

Collections

Department of Electrical and Electronics Engineering, Conference / Seminar

Suggestions

OpenMETU
Core

Unilateral deep brain stimulation suppresses alpha and beta oscillations in sensorimotor cortices Abbasi, Omid; Hirschmann, Jan; Storzer, Lena; Özkurt, Tolga Esat; Elben, Saskia; Vesper, Jan; Wojtecki, Lars; Schmitz, Georg; Schnitzler, Alfons; Butz, Markus (2018-07-01) Deep brain stimulation (DBS) is an established therapy to treat motor symptoms in movement disorders such as Parkinson's disease (PD). The mechanisms leading to the high therapeutic effectiveness of DBS are poorly understood so far, but modulation of oscillatory activity is likely to play an important role. Thus, investigating the effect of DBS on cortical oscillatory activity can help clarifying the neurophysiological mechanisms of DBS. Here, we aimed at scrutinizing changes of cortical oscillatory activit...
Evaulation of spatial and spatio-temporal regularization approaches in inverse problem of electrocardiography Önal, Murat; Serinağaoğlu Doğrusöz, Yeşim; Department of Electrical and Electronics Engineering (2008) Conventional electrocardiography (ECG) is an essential tool for investigating cardiac disorders such as arrhythmias or myocardial infarction. It consists of interpretation of potentials recorded at the body surface that occur due to the electrical activity of the heart. However, electrical signals originated at the heart suffer from attenuation and smoothing within the thorax, therefore ECG signal measured on the body surface lacks some important details. The goal of forward and inverse ECG problems is to r...
Tissue Engineered, Guided Nerve Tube Consisting of Aligned Neural Stem Cells and Astrocytes Yucel, Deniz; Kose, Gamze Torun; Hasırcı, Vasıf Nejat (2010-12-01) Injury of the nervous system, particularly in the spinal cord, impairs the quality of life of the patient by resulting in permanent loss of neurologic function. The main limitation in spinal cord regeneration is the lack of extracellular matrix to guide nerves for functional recovery of the transected nerve tissue. In the present study, a tissue engineered nerve tube was prepared by wrapping neural stem cells (NSCs) on aligned fibers using a micropatterned film with astrocytes aligned along the microgrooves...
Study on the influence of scaffold inner organization on the treatment of spinal cord injury Dursun, Tuğba; Hasırcı, Deniz; Yücel, Deniz; Department of Biotechnology (2013) Permanent loss of neurologic function occurs when the central nervous system (CNS) is injured. Nerve regeneration is extremely limited because of dense scar tissue formation at the lesion site, especially in the spinal cord. For the treatment of this type of injury, different strategies are needed. The emerging approach to solve these problems is to provide a physical support via tubular bridging devices such as “nerve guides”. They are used to bridge the neural gaps in the treatment of spinal cord injury, ...
In vitro and in vivo evaluation of doxycycline-chondroitin sulfate/PCLmicrospheres for intraarticular treatment of osteoarthritis AYDIN, Ozlem; KORKUSUZ, FEZA; KORKUSUZ, PETEK; Tezcaner, Ayşen; BİLGİÇ, ELİF; Yaprakci, Volkan; Keskin, Dilek (2015-08-01) Osteoarthritis (OA) is a degenerative joint disease, which has no complete treatment with medication yet. Intraarticular hyaluronan (HA) injection can decrease pain and modify the natural course of OA. This study was designed to provide long term delivery of an MMP (matrix-metalloproteinase) inhibitor agent-doxycycline, together with matrix regenerative agent-chondroitin sulfate for treating OA which progress with matrix degenerations. Doxycycline (D) and doxycycline-chondroitin sulfate (D-CS) loaded poly--...

Citation Formats

C. Durlu, R. Zengin, N. G. Gençer, and F. Kucukdeveci, “Numerical analysis of spinal cord stimulation with triple leads with guarded cathode,” 2015, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/46880.