Ti6Al4V foams having nanotubular surfaces for orthopaedic applications

2019-07-26
Izmir, Merve
Tufan, Yiğithan
Tan, Guher
Ercan, Batur
Despite the widespread use of Ti6Al4V in orthopaedics, the bioinert nature of this alloy limits its biological fixation with the bone tissue. To enhance its bone fixation, two different types of Ti6Al4V foams were fabricated, and their surfaces were modified zto possess nanofeatures. To prepare the foams, spherical- or irregular-shaped Ti6Al4V particles were used to form the backbones of the foams, while magnesium or carbamide powders were used as space holder agents. Once Ti6Al4V foams were fabricated, oxide-based nanotubular arrays having 40 nm diameter were formed on the interconnected pore surfaces via anodization. Results showed successful growth of nanotubular oxide arrays independent of the pore surface morphology, chemistry, and porosity content. Nanotubular surfaces induced formation of calcium phosphate minerals independent of the Ti6Al4V particle type and the space holder agent. Thus, anodized nanotubular Ti6Al4V foams could potentially induce enhanced integration of Ti6Al4V-based porous implants with the bone tissue.
SURFACE AND INTERFACE ANALYSIS

Suggestions

Viscoelastic characteristics of chain extended/branched and linear polyethylene terephthalate resins
Yılmazer, Ülkü; Xanthos, M; Bayram, Göknur; Tan, V (Wiley, 2000-03-01)
Two chemically modified chain extended/branched polyethylene terephthalate (PET) resins and one unmodified resin, considered to be linear, were characterized in terms of their melt flow, die swell, and viscoelastic properties. The three resins had reportedly similar nominal intrinsic viscosities but exhibited different viscoelastic behavior. The modified resins had lower melt flow index, higher die swell, higher complex viscosity and higher storage modulus than the unmodified one. The Cole-Cole plots of the...
Synthesis of calcium carbonate microspheres via inert gas bubbling for orthopedic applications
Oral, Cagatay M.; Caliskan, Arda; Goctu, Yagmur; KAPUSUZ, DERYA; Ercan, Batur (Elsevier BV, 2020-02-15)
Calcium carbonate (CaCO3) microspheres consisting of vaterite polymorph have been widely used in biomedical applications. Specifically, vaterite microspheres having hollow cores showed significant potential in drug delivery, however the spontaneous transformation of vaterite to other polymorphs in aqueous environments reduced its controlled in vivo release capability. In this work, calcite and aragonite microspheres having hollow/porous inner cores were synthesized -for the first time-using sodium dodecyl s...
Facile control of hydroxyapatite particle morphology by utilization of calcium carbonate templates at room temperature
Oral, Çağatay M.; Çalışkan, Arda; Kapusuz, Derya; Ercan, Batur (Elsevier BV, 2020-09-01)
Hydroxyapatite (HAp, Ca-10(PO4)(6)(OH)(2)) particles are widely used in orthopedic applications due to their chemical resemblance to the inorganic component of bone tissue. Since physical and chemical properties of HAp particles influence bone regeneration, various synthesis techniques were developed to precisely control the particle properties. However, most of these techniques required high reaction temperatures, which limited the spectrum of obtained HAp particle morphologies. In this study, ellipsoidal,...
Hydroxyl-Terminated Poly(urethane acrylate) as a Soft Liner in Dental Applications: Synthesis and Characterization
Keskin, Selda; Usanmaz, Ali (Wiley, 2010-07-05)
Hydroxyl-terminated poly(urethane acrylate)s were synthesized for use in biomedical applications. Acrylate end capping via an interesterification reaction was successfully achieved with methacryloyl chloride addition to the hydroxyl ends of the polyurethane at low temperatures. 2,4-Toluene diisocyanate, 1,6-hexane diisocyanate, and methylene diphenyl diisocyanate were used as diisocyanates for urethane synthesis, and they were end-capped with methyl methacrylate and hydroxyethyl methacrylate. The nature of ...
Tensile Bond Strength of a Highly Cross-Linked Denture Tooth to the Compression-Molded and Injection-Molded Denture Base Polymers
DOĞAN, ARİFE; Korkmaz, Turan; DOĞAN, ORHAN MURAT; Keskin, Selda; DEMİR, HAKAN (Informa UK Limited, 2009-01-01)
This study compared tensile bond strengths between conventional compression-molded heat (HC)-, auto (AP)-, and microwave-polymerized (MC) poly(methyl methacrylate)-based denture resins and a relatively new injection-molded, microwave-polymerized polyurethane based resin (MI) bonded to a highly cross-linked denture tooth. In the first part of the experiments, denture teeth were used as received. In the second part, they were treated with dichloromethane to see its effect on bonding of conventional denture ba...
Citation Formats
M. Izmir, Y. Tufan, G. Tan, and B. Ercan, “Ti6Al4V foams having nanotubular surfaces for orthopaedic applications,” SURFACE AND INTERFACE ANALYSIS, pp. 0–0, 2019, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/47809.