Beta-laktamaz enzim üretimi için endüstriyel biyoteknolojik proses geliştirilmesi

Genotyping of beta-casein, kappa-casein and beta-lactoglobulin genes in turkish native cattle breeds and efforts to delineate bcm-7 on human pbmc Dinç, Havva; Kence, Aykut; Department of Biology (2009) The main aim of this study is to determine genetic diversity of milk protein genes associated with milk traits, namely beta-casein, kappa-casein and betalactoglobulin, in native Turkish cattle breeds (Turkish Grey, Eastern Anatolian Red, Anatolian Black, and Southern Anatolian Red) and Turkish Holstein. Only 11% deviation from the Hardy-Weinberg equilibrium and insignificant Fis values for the populations were observed, indicating that samples are free of inbreeding. B alleles of these genes, which are posi...
Alpha tricalcium phosphate-based hybrid bone analogs: assessment of cement behaviour and mechanical properties / Alkan, Gözde; Durucan, Caner; Department of Metallurgical and Materials Engineering (2014) The main theme of this thesis was to establish materials science and chemical issues for developing a self-hardening cement system, for potential use in bone defect filling operations. The cement comprises of a ceramic powder  alpha-tricalcium phosphate (-TCP, -Ca3(PO4)2)  which hardens into inorganic ceramic part of the natural bone tissue, i.e. calcium deficient hydroxyapatite (CDHAp, Ca9(HPO4)(PO4)5(OH)) upon hydration. One of the primary objectives of this study therefore was, synthesis of phase pur...
Synthesis and reactions of alpha-keto-beta-hydroxyphosphonates Barış, Şehriban; Demir, Ayhan Sıtkı; Department of Chemistry (2007) This thesis presents synthesis and different reactions of alpha-keto-beta-hydroxyphosphonates. Toward this aim, the hydroxyl functionality of alpha-hydroxycarboxylic acids were protected with alkyl or acyl groups and then formation of acid chloride followed by the reaction with trialkylphosphite furnished protected alpha-keto-beta-hydroxyphosponates. Nucleophilic addition reactions were applied to these compounds to obtain quaternary alcohols with phosphonate functionality. The addition reactions were tried...
β-Fonksiyonel alfa-amino fosfonat türevlerinin sentezlenmesi Polat Çakır, Sıdıka; Doğan, Özdemir; Beksultanova, Nurzhan (2019-10-15) Aziridin kimyası üzerine yapılan son çalışmalar özellikle bunların asimetrik yöntemler kullanılarak sentezlenmesi ve aziridin halkalarının regioselektif halka açılım raksiyonları üzerinedir. Gerilimli olan aziridin halkası nükleofillere karşı oldukça reaktiftir ve tepkime sonunda elde edilen primer veya sekonder aminler farklı bileşiklerin sentezlenmesi için kullanılabilirler. Bu çalışmada kullanılan N-alkil sübstitue olmuş aziridinil 2-fosfonatlar aziridin kimyasında aktive olmamış aziridin grubuna girmekt...
Synthesis and Chiroptical Properties of Alpha Chiral 2,5-Diaminoterephthalates Baykal, Doruk; Akdağ, Akın; Department of Chemistry (2022-9) 2,5-Diaminoterephthalates (DATs) are known to be intensely colored and fluorescent compounds that are quite open to functionalization. Even though their conjugated structure is significantly shorter/smaller than that of its popular counterparts such as fluoresceins and BODIPYs, they possess comparable optical properties. Most prominently, DATs have been used as organic linkers for metal organic framework (MOF) materials, and as fluorescent sensors. Despite the existence of chiral DAT derivatives, their chi...

Citation Formats

P. Çalık, “Beta-laktamaz enzim üretimi için endüstriyel biyoteknolojik proses geliştirilmesi,” 2005. Accessed: 00, 2020. [Online]. Available: https://app.trdizin.gov.tr/publication/project/detail/TnpJNU1EQT0.