Genetic polymorphisms of the human cytochrome p4502e1 and nad(p)h: quinon-e oxidoreductase 1 genes and susceptibility to ischemic stroke

Association analysis of GSTO2 Asn142Asp genetic polymorphism and ischemic stroke risk in Turkish population CAN DEMİRDÖĞEN, BİRSEN; Bilgin, E.; Ozcelik, A.; Demirkaya, S.; Adalı, Orhan (2014-09-01)
Analysis of cytochrome P4501A1 genetic polymorphisms in patients with ischemic stroke Adalı, Ayşe Çınar; Adalı, Orhan; Demirdöğen, Birsen Can; Department of Biochemistry (2011) Stroke is the third leading cause of death worldwide and results in serious disabilities. Cytochrome P450 1A1 gene (CYP1A1) is a highly polymorphic gene encoding its corresponding xenobiotic metabolizing enzyme which is responsible from the metabolism of carcinogenic polycyclic aromatic hydrocarbons (PAHs) that are engaged with the formation of free radicals. Atherosclerosis is a major cause of ischemic stroke and this pathology may be associated with the disruption of vascular homeostasis due to the format...
Genetic variability among Turkish pop, flint and dent corn (Zea mays L. spp. Mays) races: Enzyme polymorphism Ilarslan, R; Kaya, Zeki; Tolun, AA; Bretting, PK (2001-01-01) To determine magnitude and pattern of genetic variation, 32 Turkish corn accessions available from the USDA/ARS North Central T-Regional Plant Introduction Station (NCRPIS) collections (Ames, Iowa), representing pop, flint and dent corn races, different climatic, geographic and topographic areas in Turkey, were identified and, 19 isozyme systems were studied. Thirty-nine alleles were detected by 19 isozyme loci in 32 accessions. The PGD-2, Mmm-1, GOT-3 and IDH-1 loci were found to be monomorphic in all acce...
Polymorphisms of epoxide hydrolase genes and ischemic stroke risk in Turkish population Miçooğulları, Yağmur; Adalı, Orhan; Can Demirdöğen, Birsen; Department of Biology (2011) Stroke is characterized with loss of one or more functions of the body resulted by inadequate blood supply to the brain. Most of the cases result from a blood clot forms on an atherosclerotic plaque in the brain which is called as ischemic stroke. Structure of the arteries and vascular tone are listed in major determinants in the development of the disorder. Soluble epoxide hydrolase (sEH, EPHX2) catalyzes conversion of epoxyeicosatrienoic acids to inactive diol metabolites. EETs are potent vasodilators tha...
Association between nitric oxide synthase 3 G894T and intron 4 VNTR genetic polymorphisms and ischemic stroke risk in Turkish population Ozcelik, A. T.; Demirdogen, B. C.; Akgun, H.; Bek, S.; Demirkaya, S.; Adalı, Orhan (2012-09-01)

Citation Formats

A. T. Ozcelik et al., “Genetic polymorphisms of the human cytochrome p4502e1 and nad(p)h: quinon-e oxidoreductase 1 genes and susceptibility to ischemic stroke,” 2011, vol. 278, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/53789.