Synthesis of highly substituted pyridines by Pd-catalyzed Sonogashira and Suzuki-Miyaura couplings of 4-iodopyridines

Zora, Metin
Kilicaslan, Nihan Zulay


Synthesis of ferrocenyl substituted quinolines
Velioğlu, Özlem; Zora, Metin; Department of Chemistry (2008)
Quinolines have been studied for over a century as an important class of heterocyclic compounds and continue to attract considerable interest due to the broad range of biological activities they possess. The incorporation of the essential structural features of quinolines with a ferrocene moiety could provide new derivatives with unexpected and/or enhanced biological activities since several ferrocene derivatives have already been shown to be active against a number of tumors. For this reason, we investigat...
Synthesis of 1,2,3,5- tetrasubstituted pyrrole derivatives via 5-exo-dig type cyclization and stereoselective functionalisation of ferrocene derivatives
Kayalar, Metin; Demir, Ayhan Sıtkı; Department of Chemistry (2005)
A convenient and new method for the synthesis of 1,2,3,5-tetrasubstituted pyrrole derivatives starting from 1,3,-dicarbonyl compounds through acid catalyzed cyclization reaction is described. Alkylation of 1,3-dicarbonyl compound with propargyl bromide followed by one step cyclization with the introduction of primary amines in the presence of catalytic amount of triflouroacetic acid (TFA) affords the corresponding pyrrole derivatives in high yields. The investigations on the studies of developing a new meth...
Synthesis of thiophene capped polytetrahydrofuran conducting copolymers
Ünür, Ece; Toppare, Levent Kamil; Department of Chemistry (2003)
Synthesis of star-shaped pyrrole and thiophene functionalized monomers and optoelectrochemical properties of corresponding copolymers
Ak, Metin; Toppare, Levent Kamil (Elsevier BV, 2009-04-15)
Star-shaped thiophene and pyrrole functionalized monomers namely 2,4,6-tris(4-(1H-pyrrol-1-yl)phenoxy)-1,3,5-triazine (TriaPy) and 2,4,6-tris(4-(1H-pyrrol-1-yl)phenoxy)-1,3,5-triazine (TriaTh) were synthesized from 2,4,6-trichloro-1,3,5-triazine, thiophen-3-ylmethanol and 4-(1H-pyrrol-1-yl)phenol. Electrochemical copolymerization of monomers with thiophene and pyrrole was achieved in tetrabutylammonium tetrafluoroborate/acetonitrile (TBAFB/AN). Resulting copolymers were characterized by Fourier transform in...
Maharramov, A. M.; Akay, P.; Akhmedov, I. M.; Safarova, A. S.; Qurbanova, M. M.; Huseynov, E. Z.; Musayeva, S. A. (2019-01-01)
It is known that pyrrole and its derivatives are a part of many important natural compounds. Polymeric semiconductors also were obtained on the basis of 2,5-dithienyl-pyrrole electropolymerization and its derivatives. The work deals with the synthesis of 2,3-dithiophenyl-1H-pyrroles by the reaction of 2,2'-thionine with various enamines.
Citation Formats
M. Zora and N. Z. Kilicaslan, “Synthesis of highly substituted pyridines by Pd-catalyzed Sonogashira and Suzuki-Miyaura couplings of 4-iodopyridines,” 2012, vol. 243, Accessed: 00, 2020. [Online]. Available: