Synthesis of 4,5-dihydropyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]quinoxaline derivatives



Synthesis of alkynyl-substituted pyrrole and 1,4-thiazepine derivatives
Yılmaz, Elif Serel; Zora, Metin; Department of Chemistry (2018)
Heterocyclic compounds have a great importance in medicinal chemistry because of their presence in a number of pharmaceuticals. Among them, pyrroles and 1,4-thiazepines play a vital role in pharmaceutical chemistry because of their presence in a number of bioactive molecules and natural products. For this reason, the development of new synthetic methods for the synthesis of these compounds has attracted much attention. Recently, the cyclization of functionally-substituted alkynes has emerged as a valuable t...
Synthesis of fused tetrazolone derivatives
Ozcan, Sevil; Ekmekci, Zeynep; Mujde, Berk; Balcı, Metin (2013-01-01)
New fused tetrazolone derivatives were synthesized using homophthalic and maleic anhydrides. Treatment of anhydrides with trimethylsilyl azide opened the lactone rings and formed the corresponding intermediates, which bore 1,3-dipole and dipolarophile functionalities in ortho positions. The intermediates partially underwent internal 1,3-dipolar cycloaddition to produce fused tetrazolone derivatives. When the carbonyl groups in anhydride were not conjugated with any double bond, then a triazine-fused tetrazo...
Synthesis of Ferrocenyl Substituted Aziridines
Zeytinci, Serhat; Doğan, Özdemir; Department of Chemistry (2006)
Immobilization of tyrosinase enzyme was performed in the matrices obtained via copolymerization of terephthalic acid bis-(2-thiophen-3-yl ethyl) ester (TATE) with pyrrole. During electrochemical polymerization of pyrrole, enzyme molecules were entrapped in the copolymer matrice. Activity measurements were performed by using Besthorn̕s Hydrazone method which includes spectrophotometric analysis of quinones produced by the enzyme. Enzyme electrodes were characterized in terms of maximum reaction rate (Vmax) a...
Synthesis of various camphor-based chiral pyridine derivatives
Işık, Murat; Tanyeli, Cihangir; Department of Chemistry (2005)
Chiral aromatic nitrogen heterocycles are finding many applications in asymmetric organic synthesis, particularly as ligands in the preparation of chiral metal complexes. Since camphor-based chiral auxiliaries are known to be especially effective, a number of pyridines fused to the camphor skeleton have been reported. It is well known that nicotinic acid and its derivatives exhibiting qualitatively the biological activity of nicotinamide, which acts as an electron acceptor in many biological redox reactions...
Synthesis of various camphor-based chiral pyridine derivatives
Tanyeli, Cihangir; Isik, M (Elsevier BV, 2004-07-19)
(+)-beta-Hydroxymethylenecamphor 1 and enamines 2a-e were transformed into chiral camphor-based pyridine derivatives 3a-e via a tandem condensation reaction in good yields.
Citation Formats
M. Zora, “Synthesis of 4,5-dihydropyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]quinoxaline derivatives,” 2012, vol. 243, Accessed: 00, 2020. [Online]. Available: