Transition metal compound mediated reduction of alpha-amino acids to 1,2-amino alcohols with NaBH4 in water

Demir, Ayhan Sıtkı
Akhmedov, IM
Sesenoglu, O
A new efficient and cost-effective method for the preparation of 1,2-amino alcohols is described. The reactions of amino acids with NaBH4 in the presence of NiCl2 or MoO3 in water give 1,2-amino alcohols in high yield. When optically pure amino acids were used, optically pure 1,2-amino alcohols were obtained.


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Simple, mild, and efficient method for the reduction of 1,4-benzoquinones to hydroquinones by the action of NaN3
Algi, Fatih; Balcı, Metin (Informa UK Limited, 2006-08-01)
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Citation Formats
A. S. Demir, I. Akhmedov, and O. Sesenoglu, “Transition metal compound mediated reduction of alpha-amino acids to 1,2-amino alcohols with NaBH4 in water,” TURKISH JOURNAL OF CHEMISTRY, pp. 123–126, 1999, Accessed: 00, 2020. [Online]. Available: