A 1 : 1 cocrystal of (1R,3S,4S,6R)-1,2,3,4,5,6-hexabromo-1,2,3,4,5,6-hexahydropentalene and (1R,2R,4S,5S)-1,2,3,4,5,6-hexabromo-1,2,4,5-tetrahydropentalene

Date

2006-06-01

Author

Hokelek, Tuncer
Gunbas, Duygu D.
Algi, Fatih
Balcı, Metin

Metadata

Show full item record

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Item Usage Stats

126
views

0
downloads

The components of the title compound, C8H6Br6 and C8H4Br6, are hexa- and tetrabromopentalene derivatives, which were obtained by the treatment of hexahydropentalene with a tenfold excess of bromine. The asymmetric unit consists of two half-mol-ecules. Crystallographic centres of symmetry are located at the mid-points of the central C=C and C-C bonds. The repulsive inter-actions between the Br atoms may affect the mol-ecular geometry.

Subject Keywords

High-temperature bromination, Saturated-hydrocarbons, Derivatives, Functionalization, Benzobarrelene

URI

https://hdl.handle.net/11511/57837

Journal

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS

DOI

https://doi.org/10.1107/s1600536806012645

Collections

Graduate School of Natural and Applied Sciences, Article

Suggestions

OpenMETU
Core

Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population Ulusoy, Gülen; Adalı, Orhan; Department of Biochemistry (2004) Cytochrome P4502E1 (CYP2E1), the ethanol-inducible isoform of cytochrome P450 superfamily, catalyzes many low molecular weight endogenous and exogenous compounds, including ethanol, acetone, drugs like acetaminophen and chlorzoxazone, and industrial solvents like benzene and styrene, most of which are carcinogenic. Besides, it has a high capacity to produce reactive oxygen species. CYP2E1 is induced by ethanol and isoniazid, as well by some pathophysiological conditions like diabetes and starvation. CYP2E1 ...
Molecular recognition of poly(A) by small ligands: an alternative method of analysis reveals nanomolar, cooperative and shape-selective binding Persil Çetinkol, Özgül (Oxford University Press (OUP), 2009-02-01) A few drug-like molecules have recently been found to bind poly(A) and induce a stable secondary structure (T(m)approximate to 60 degrees C), even though this RNA homopolymer is single-stranded in the absence of a ligand. Here, we report results from experiments specifically designed to explore the association of small molecules with poly(A). We demonstrate that coralyne, the first small molecule discovered to bind poly(dA), binds with unexpectedly high affinity (K(a) >10(7) M(-1)), and that the crescent sh...
Regioselectivity observed in manganese(III) acetate mediated addition of acetylacetone to various alkenes: mechanistic and theoretical studies Ceyhan, Selin; Cetinkaya, Yasin; Akdağ, Akın; BALCI, METİN (2016-10-27) Various alkenes substituted at the 1,2-positions by 2-thiophenyl, 3-thiophenyl, and phenyl substituted by electron-withdrawing and electron-donating groups were treated with acetylacetone in the presence of Mn(OAc)(3) in acetic acid. In cases where the thiophene ring was connected at the C-2 carbon atom to the double bond, a single regioisomer was formed whereas in case of substitution at the C-3 positions two regioisomers were formed. Stilbene derivatives also gave two regioisomers under the same reaction ...
Cloning and expression of periplasmic (clp p-like) and membrane-bound serine protease genes of thermoplasma volcanium in escherichia coli Demirok, Burçak; Kocabıyık, Semra; Department of Biology (2006) Serine proteases are a family of proteases that utilize an activated serine residue in the substrate-binding pocket to catalytically hydrolyze peptide bonds. Enzymes which belong to this family, with a diverse array of metabolic and regulatory functions, play critical roles in cell physiology and pathology. ءClp̕s are a class of ATP dependent serine proteases which are composed of a protease (ClpP) and an ATPase (ClpA or ClpX) component. Their involvements in degrading proteins are especially implicated und...
Enantioselective Friedel-Crafts alkylation of indole with nitroalkenes in the presence of bifunctional squaramide organocatalysts Dündar, Esra; Tanyeli, Cihangir (2021-01-01) A series of chiral bifunctional quinine and 2-aminoDMAP based squaramide organocatalysts are evaluated in Friedel-Crafts alkylation of indoles with nitroolefins. These 3-substituted indole derivatives are synthesized in the presence of sterically encumbered tert-butyl squaramide/quinine with high enantioselectivity (up to >99% ee) and moderate chemical yields (up to 80%) by representing as chiral precursors for very important biologically active molecules. Besides, this asymmetric transformation provides a ...

Citation Formats

T. Hokelek, D. D. Gunbas, F. Algi, and M. Balcı, “A 1 : 1 cocrystal of (1R,3S,4S,6R)-1,2,3,4,5,6-hexabromo-1,2,3,4,5,6-hexahydropentalene and (1R,2R,4S,5S)-1,2,3,4,5,6-hexabromo-1,2,4,5-tetrahydropentalene,” ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, pp. 0–0, 2006, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/57837.