Matrix entrapment of glucose oxidase by gamma irradiation

Gürsel, İhsan


GURSEL, I; Hasırcı, Vasıf Nejat (1992-01-01)
In this study, matrix entrapment of the enzyme glucose oxidase was achieved through gamma-irradiation of monomers N-vinyl pyrrolidone, 2-hydroxyethyl methacrylate and their mixture. To test the effect of radiation on entrapment efficiency, retention of activities and properties of the system, duration and temperature were varied. The reusability of the resultant products was tested. It was generally found that inclusion of the hydrophilic monomer N-vinyl pyrrolidone into the matrix increased the water conte...
Matrix fracture interaction in sandstone rocks during carbon dioxide, methane and nitrogen injection
Bülbül, Sevtaç; Parlaktuna, Mahmut; Department of Petroleum and Natural Gas Engineering (2012)
The aim of the study is to investigate matrix-fracture interaction, gas oil gravity drainage (GOGD) and diffusion mechanisms with CO2, N2 and CH4 gas injection in a fractured system. Effects of injected gas type, initial gas saturation and diffusion coefficient on oil recovery are studied by an experimental and simulation work. In the experimental study, Berea sandstone cores are placed in a core holder and the space created around the core is considered as a surrounding fracture. System is kept at a pressu...
Matrix metalloprotease 16 expression is downregulated by microRNA-146a in spontaneously differentiating Caco-2 cells
ASTARCI, ERHAN; Erson Bensan, Ayşe Elif; Banerjee, Sreeparna (2012-02-01)
Cellular differentiation in the gut is vital in maintaining the cellular and functional specialization of the epithelial layer. MicroRNAs (miRNAs) have recently emerged as one of the key players in orchestrating the differentiation process in the gut. Using the spontaneously differentiating Caco-2 cell line, we observed an increased expression of miR-146a but not miR-146b in the course of differentiation. Bioinformatic analyses revealed that the membrane type matrix metalloprotease 16 (MMP16, MT3-MMP) was a...
Surface functionalization of sba-15 particles for celecoxib delivery
Gezer, Gamze; Yılmaz, Ayşen; Department of Chemistry (2013)
Mesoporous silica particles have been used to enhance the loading capacity of drugs into these particles, increase bioavailability and control drug release. In this study SBA-15 particles were synthesized and functionalized to improve the loading capacity and release rate of drug. Then, drug loading and release process were investigated. Celecoxib was chosen as a model drug which is very hydrophobic. SBA-15 particles were used due to their highly ordered, well-defined mesoporous structure. These particles w...
Surface functionalization of SBA-15 particles for amoxicillin delivery
Sevimli, Filiz; Yılmaz, Ayşen (2012-08-01)
The hydrothermally synthesized SBA-15 particles were surface functionalized by post-grafting synthesis method with (3-aminopropyl) triethoxy silane, mercaptopropyl trimethoxy silane and triethoxy methyl silane in order to be used as carrier materials for drug delivery. Amoxicillin was used as a model drug. The adsorption and release properties of calcined and organic-functionalized mesoporous silicas containing terminal primary amine, organothiol and methyl groups toward amoxicillin have been investigated. ...
Citation Formats
İ. Gürsel, “Matrix entrapment of glucose oxidase by gamma irradiation,” Middle East Technical University, 1989.