The detection of mutagenic activity of some chemicals (Azamethyphos, Dichlorvos, Methyl parathion, Aflatoxin B-1) by SMART Drosophila melanogaster

Date

2000-01-01

Author

Ekebas, S
Cakir, S
Ertugrul, O
Kence, Aykut

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In this study mutagenic effects of some chemicals used in Veterinary Medicine and agricultural fields was investigated by Somatic Mutation and Recombination Test (SMART). SMART test was to observe the chemical effects on wing phenotype of the trans- heterozygote flies carrying marker gene. Lethal doses of the chemicals used were determined. A positive correlation was observed between total mutation and the number of wings having mutations. In addition, the observed mutations were classified according to the size and the type of the mutations per wing. Chemicals used were ranked as Dichlorvos, Methyl parathion, Azamethyphos according to their genotoxic effects. The present study pointed out that the correct administration of pesdicides has significant effect on human and enviromental health which are under the threat of hazardous pesticid residues.

Subject Keywords

Drosophila melanogaster, Somatic mutation and recombination test, Genetic toxicology

URI

https://hdl.handle.net/11511/62920

Journal

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES

Collections

Department of Biology, Article

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Citation Formats

S. Ekebas, S. Cakir, O. Ertugrul, and A. Kence, “The detection of mutagenic activity of some chemicals (Azamethyphos, Dichlorvos, Methyl parathion, Aflatoxin B-1) by SMART Drosophila melanogaster,” TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, pp. 563–569, 2000, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/62920.