CYP1A1 from genes to enzymes and biological effect monitoring

Arinc, E.


CYP2E1 *5B and *6 polymorphisms are possible risk factors in the development of childhood acute lymphoblastic leukemia
Ulusoy, Gulen; Adalı, Orhan; Tumer, Tugba Boyunegmez; Sahin, Gurses; Gozdasoglu, Sevgi; Arinc, Emel (2006-01-01)
Cytokine polymorphism catalog (cytocat) for the analysis of phenotype associations
Oğuz, Gökçe; Acar, Aybar Can; Aydın Son, Yeşim; Department of Bioinformatics (2014)
Currently, many studies focus on identifying disease related biological biomarkers for prediction of susceptibility, early detection, and prevention, in addition to developing new therapeutic approaches. In our study, we have investigated the single nucleotide polymorphisms (SNPs) of human cytokines and cytokine receptors, which play an important role in the immune system, as potential disease biomarkers and focused on phenotypes as they might give clue about disease symptoms. Our main aim was to create a c...
Cytotoxic dose assessment of cell stress inducers on human bone marrow mesenchymal stem cells by real-time xCELLigence impedance analysis
Aygar, S.; BALTA, GÜNAY; ÇELEBİ SALTIK, BETÜL; KILIÇ, ESRA; Cetinkaya, D. Uckan (2016-09-01)
Cytochrome P4501A1 genotypes and smoking- and hypertension-related ischemic stroke risk
Demirdöğen, B. Can; Adali, A.Ç.; Bek, S.; Demirkaya, Ş.; Adalı, Orhan (SAGE Publications, 2012-10-30)
This study aimed to determine whether the coding (A4889G) and noncoding region (T6235C) polymorphisms of the gene coding for cytochrome P4501A1 (CYP1A1), a xenobiotic-metabolizing enzyme responsible for the metabolism of carcinogenic polycyclic aromatic hydrocarbons, are involved in the pathogenesis of ischemic stroke in Turkish population. Study group consisted of 226 ischemic stroke patients and 113 controls. Genotypes were attained by allele-specific polymerase chain reaction (PCR) for A4889G and PCR/res...
Cytochrome P4502B-type protein from feral leaping mullet (Liza Saliens) liver microsomes: its isolation and biochemical and immunological characterization
Bozcaarmutlu, Azra; Arınç, Emel; Department of Biochemistry (2002)
Cytochrome P450s constitute a superfamily of hemoproteins that play important roles in oxidative metabolism of endogenous and exogenous compounds, and serve as catalysts that are significant in numerous and diverse biological pathways. The extent to which these various pathways or functions occur in different animal groups depend on a large degree on the participation of different P450 proteins present, their catalytic function and their regulation. Cytochrome P4502B subfamily is generally associated with d...
Citation Formats
E. Arinc, “CYP1A1 from genes to enzymes and biological effect monitoring,” 2006, vol. 273, p. 36, Accessed: 00, 2020. [Online]. Available: