Dursun, I.
Jakubowska-Dogru, E.
Chalupa, L. M.
Berman, R. F.


Effects of early postnatal alcohol exposure on the developing retinogeniculate projections in C57BL/6 mice
DURSUN, İLKNUR; Jakubowska-Dogru, Ewa; Elibol-Can, Birsen; van der List, Deborah; Chapman, Barbara; Qi, Lihong; Berman, Robert F. (Elsevier BV, 2013-05-01)
Previous studies on the adverse effects of perinatal exposure to ethanol (EtOH) on the developing visual system mainly focused on retinal and optic nerve morphology. The aim of the present study was to investigate whether earlier reported retinal and optic nerve changes are accompanied by anomalies in eye-specific fiber segregation in the dorsal lateral geniculate nucleus (dLGN). C57BL/6 mice pups were exposed to ethanol by intragastric intubation at either 3 or 4 g/kg from postnatal days (PD) 3-10, the thi...
Effects of chronic ethanol consumption on memory and molecular changes in the hippocampus of young adult Wistar rats
Elibol, Birsen; Doğru, Ewa; Department of Biology (2007)
The aim of the present study was to examine retention of spatial reference memory after 6 (Experiment I) and 15days (Experiment II) of binge-like drinking and during alcohol withdrawal in young adult Wistar rats. Prior to alcohol treatment, rats received Morris Water Maze (MWM) training. Afterwards, rats were intragastrically administered ethanol at the dose increasing from 4.5g-to-12g/kg. Intubation control groups (n=7 and n=10, respectively) received infusions of a sucrose solution without ethanol. Subseq...
Effects of chronic intracerebroventricular administration of rat recombinant NGF on spatial working memory in adult memory-deficient rats
Gümüşbaş, Umut; Jakubowska-Doğru, Ewa; Department of Biological Sciences (2002)
Effects of fetal alcohol and maternal intubation stress on the expression of proteins controlling postnatal development of male rat hippocampus
ELİBOL, BİRSEN; BEKER, MERVE; Jakubowska-Dogru, Ewa; KILIÇ, ÜLKAN (Informa UK Limited, 2020-09-01)
Background Developing brains can partially get over prenatal alcohol exposure-related detrimental conditions by activating some mechanisms involved in survival. Objectives This study aimed to shed light on the molecular correlates of compensatory mechanisms by examining temporal profiles in the expression of proteins controlling postnatal development in the rat hippocampus prenatally exposed to intubation stress/ethanol. Methods Male pups were randomly assigned to age subgroups (n = 21/age) which were sacri...
Effects of prenatal binge-like ethanol exposure and maternal stress on postnatal morphological development of hippocampal neurons in rats
Jakubowska-Dogru, Ewa; Elibol, Birsen; Dursun, Ilknur; Yuruker, Sinan (Wiley, 2017-10-01)
Background: Alcohol is one of the most commonly used drugs of abuse negatively affecting human health and it is known as a potent teratogen responsible for fetal alcohol syndrome (FAS), which is characterized by cognitive deficits especially pronounced in juveniles but ameliorating in adults. Searching for the potential morphological correlates of these effects, in this study, we compared the course of developmental changes in the morphology of principal hippocampal neurons in fetal-alcohol (A group), intub...
Citation Formats
I. Dursun, E. Jakubowska-Dogru, L. M. Chalupa, and R. F. Berman, “EFFECTS OF NEONATAL ALCOHOL EXPOSURE ON THE DEVELOPING DORSAL LATERAL GENICULATE NUCLEUS IN C57BL/6 MICE,” 2009, vol. 33, p. 0, Accessed: 00, 2020. [Online]. Available: https://hdl.handle.net/11511/67516.