Space-Resolved Brain Tissue Analysis by Solid Phase Microextraction Coupled to High Resolution Mass Spectrometry Via Desorption Electrospray Ionization

Date

2018-02-26

Author

Lendor, Sofia
Boyacı, Ezel
Gómez-ríos, German A
Vander Heide, Harmen
Pawliszyn, Janusz

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https://hdl.handle.net/11511/71469

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Space-resolved tissue analysis by solid-phase microextraction coupled to high-resolution mass spectrometry via desorption electrospray ionization Lendor, Sofia; Gómez-Ríos, Germán Augusto; Boyacı, Ezel; Vander Heide, Harmen; Pawliszyn, Janusz (American Chemical Society (ACS), 2019-08-06) It is hard to overstate the tremendous utility of desorption electrospray ionization (DESI) and its various configurations for rapid and high-throughput analyses or spatially resolved imaging of heterogeneous systems. However, there have been few attempts to employ this technique in spatially resolved mode with solid substrates featuring extractive and analyte-enrichment properties. This study documents the development of a platform that combines solid-phase microextraction (SPME) with desorption electrospr...
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Citation Formats

S. Lendor, E. Boyacı, G. A. Gómez-ríos, H. Vander Heide, and J. Pawliszyn, “Space-Resolved Brain Tissue Analysis by Solid Phase Microextraction Coupled to High Resolution Mass Spectrometry Via Desorption Electrospray Ionization,” 2018, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/71469.