Impaired Toll Like Receptor-7 and 9 Induced Immune Activation in Chronic Spinal Cord Injured Patients Contributes to Immune Dysfunction

2017-04-25
Güçlüler, Gözde
Adıgüzel, Emre
Güngör, Bilgi
Kahraman, Tamer
Gürsel, Mayda
Yılmaz, Bilge
Gürsel, İhsan

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Reduced immune activation or immunosuppression is seen in patients withneurological diseases. Urinary and respiratory infections mainly manifested as septicemia and pneumonia are the most frequent complications following spinal cord injuries and they account for the majority of deaths. The underlying reason of these losses is believed to arise due to impaired immune responses to pathogens. Here, we hypothesized that susceptibility to infections of chronic spinal cord injured (SCI) patients might be due to i...
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Citation Formats
G. Güçlüler et al., “Impaired Toll Like Receptor-7 and 9 Induced Immune Activation in Chronic Spinal Cord Injured Patients Contributes to Immune Dysfunction,” 2017, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/73056.