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Improvement Solubility of Celecoxib by Inclusion in LP-PEI-SBA-15 Mesoporous Silica: Drug Loading and Release
Date
2017-07-06
Author
Yılmaz, Ayşen
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URI
https://hdl.handle.net/11511/73727
Conference Name
NATO/NANOAPP Conference 2017, (14-18 Haziran 2017)
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Unverified, Conference / Seminar
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Improved solubility of celecoxib by inclusion in SBA-15 mesoporous silica: Drug loading in different solvents and release
Eren, Zeynep Seda; Tuncer, Sinem; Gezer, Gamze; Yildirim, Leyla Tatar; Banerjee, Sreeparna; Yılmaz, Ayşen (2016-11-15)
In this study, celecoxib (CLX), a highly hydrophobic nonsteroidal anti-inflammatory drug with relatively low bioavailability, was used as a model drug to determine loading in different solvents and release properties from silica particles. Hydrothermal synthesis method was used to synthesize SBA-15 particles, which were functionalized by post-synthesis grafting method with (3-Aminopropyl) triethoxysilane (APTES). Additionally, boron doped SBA-15 samples were prepared to generate borosilicate samples. After ...
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A. Yılmaz, “Improvement Solubility of Celecoxib by Inclusion in LP-PEI-SBA-15 Mesoporous Silica: Drug Loading and Release,” presented at the NATO/NANOAPP Conference 2017, (14-18 Haziran 2017), 2017, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/73727.