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Bordetella pertussis Tohama I ve Saadet suşuna ait PPIase, POMP ve FIMX genlerinin klonlanması
Date
2009-12-13
Author
Özcengiz, Gülay
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https://hdl.handle.net/11511/76374
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Bordetella pertussis’e ait rekombinant dış membran protein Q, demir süperoksit dismutaz ve putatif lipoproteinin immün koruyucu kapasitelerinin değerlendirilmesi
Özcengiz, Gülay (null; 2017-10-05)
Immune responses against the recombinant FimX and putative peptidyl-prolyl cis-trans isomerase from Bordetella pertussis
Yılmaz, Çiğdem; Özcengiz, Gülay; Department of Biology (2011)
Whooping cough (pertussis) is a highly contagious respiratory infection caused by Bordetella pertussis. It becomes widespread among adolescent and adults as well as infants. Although availability of effective pertussis vaccines seems to decrease the incidence of the disease, B. pertussis circulation in population has not been eliminated. It is thought that the antigenic drifts in major protective antigens and continued circulation of B. pertussis strains will result in gradual loss of the efficacy of the cu...
Assessment of immune protective capacities of the recombinant outer membrane protein q, iron superoxide dismutase and putative lipoprotein from bordetella pertussis
Yılmaz, Çiğdem; Özcengiz, Gülay; Department of Biology (2017)
Pertussis is a contagious disease which is commonly seen among infants and children and caused by a human pathogen known as Bordetella pertussis. There are currently two vaccine types available against the disease; whole-cell (wP) and acellular pertussis (aP) vaccines. Due to the side effects of wP vaccine, aP vaccines are commonly preferred for vaccination. Despite high vaccination coverage, high incidence rates among adolescents and adults have been reported causing the resurgence of pertussis to be the f...
Analysis of cross-immune reaction between strains of Bordetella Pertussis
İşcan, Elvin; Özcengiz, Gülay; Department of Biochemistry (2009)
Bordetella pertussis is the causative agent of whooping cough which is a worldwide acute respiratory disease that predominantly involves infants. Whooping cough is one of the ten most common causes of death from infectious diseases worldwide. The increased coverage of the primary pertussis vaccination (DaBT-IPA-Hib) decreased the incidence of disease in Turkey dramatically. However, in spite of the incidence decline, the circulation of B. pertussis has not yet been eliminated, and a change in the clinical s...
Towards whole cell immunoproteome and subproteomes of bordetella pertussis
Tefon, Burcu Emine; Özcengiz, Gülay; Department of Biology (2012)
Bordetella pertussis is a gram-negative, human pathogen and etiologic agent of whooping cough (pertussis), a highly contagious, acute respiratory illness. In this study, the analysis of whole immunproteome and subproteomes of this microorganism was performed. The soluble cytoplasmic proteomes of B. pertussis Tohama I strain and a local isolate Saadet were separated by 2DE. By Western blot analysis, we identified 25 immunogenic proteins of three categories. In the first group, there were well-known proteins ...
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G. Özcengiz, “Bordetella pertussis Tohama I ve Saadet suşuna ait PPIase, POMP ve FIMX genlerinin klonlanması,” 2009, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/76374.