Preparation and characterisation of chitosan/silver nanowires scaffolds for tissue engineering applications

Aydın, Dilara
Aksoy, Eda Ayşe
Doğanay, Doğa
Ünalan, Hüsnü Emrah
Şenel, Sevda


Preparation and Characterization of Chitosan and PLGA-Based Scaffolds for Tissue Engineering Applications
Endoğan Tanır, Tuğba; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin (2015-10-01)
Three dimensional (3D) biodegradable porous scaffolds play a crucial role in bone tissue repair. In this study, four types of 3D polymer/hydroxyapatite (HAp) composite scaffolds were prepared by freeze drying technique in order to mimic the organic/inorganic nature of the bone. Chitosan (CH) and poly(lactic acid-co-glycolic acid) (PLGA) were used as the polymeric part and HAp as the inorganic component. Properties of the resultant scaffolds, such as morphology, porosity, degradation, water uptake, mechanica...
Preparation and evaluation of polymer based microcarriers for hydrophobic anti-cancer drugs
Demetçi, Demet; Gündüz, Ufuk; Department of Biotechnology (2007)
Chemotherapy is one of the most important treatments for cancer. However, systemic toxicity, drug resistance and unstable kinetics of the drug in the blood are serious problems of chemotherapy. The use of biodegradable polymers for controlled release of anticancer drugs has gained popularity in recent years. Controlled release of drugs from polymeric carriers has some advantages such as improvement in the efficiency of treatment, reduction in systemic toxicity and prevention of the drug resistance that is d...
Preparation and characterization of chitosanpolyethylene glycol microspheres and films for biomedical applications
Günbaş, İsmail Doğan; Hasırcı, Nesrin; Department of Polymer Science and Technology (2007)
In recent years, biodegradable polymeric systems have gained importance for design of surgical devices, artificial organs, drug delivery systems with different routes of administration, carriers of immobilized enzymes and cells, biosensors, ocular inserts, and materials for orthopedic applications. Polysaccharide-based polymers represent a major class of biomaterials, which includes agarose, alginate, dextran, and chitosan. Chitosan has found many biomedical applications, including tissue engineering, owing...
Preparation and characterization of chitosan-gelatin/hydroxyapatite scaffolds for hard tissue engineering approaches
Işıklı, Cansel; Hasırcı, Nesrin; Department of Biomedical Engineering (2010)
Hard tissue engineering holds the promise of restoring the function of failed hard tissues and involves growing specific cells on extracellular matrix (ECM) to develop „„tissue-like” structures or organoids. Chitosan is a linear amino polysaccharide that can provide a convenient physical and biological environment in tissue regeneration attempt. To improve chitosan‟s mechanical and biological properties, it was blended with another polymer gelatin. 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) and N-...
Preparation and performance analysis of acrylonitrile based nanocomposite membranes for chromium (VI) removal from aqueous solutions
Bozkır, Selçuk; Usanmaz, Ali; Sankır, Mehmet; Department of Polymer Science and Technology (2010)
Acrylonitrile were copolymerized with 2-ethylhexyl acrylate and hexyl acrylate via one step emulsion polymerization using ammonium persulfate (initiator), 1-dodecanthiol (chain transfer agent) and DOWFAX 8390 (surfactant) in the presence of water at about 68 0C. Poly (acrylonitrile-2ethylhexyl acrylate) and poly (acrylonitrile-hexyl acrylate) copolymers with three different comonomer composition (8, 12 and 16 molar percent) were prepared. FTIR and 1H-NMR were used in order to clarify the chemical structure ...
Citation Formats
D. Aydın, E. A. Aksoy, D. Doğanay, H. E. Ünalan, and S. Şenel, “Preparation and characterisation of chitosan/silver nanowires scaffolds for tissue engineering applications,” presented at the International Pharmaceutical Technology Symposium-IPTS-2018, (17 - 19 Eylül 2018), 2019, Accessed: 00, 2021. [Online]. Available: