Crosslinked Pullulan Cellulose Acetate Electrospun Scaffolds for Bone Tissue Engineering

Atila, Deniz Hazal
Keskin, Dilek
Tezcaner, Ayşen


Crosslinked pullulan/cellulose acetate fibrous scaffolds for bone tissue engineering
Atila, Deniz; Keskin, Dilek; Tezcaner, Ayşen (2016-12-01)
Natural polymer based fibrous scaffolds have been explored for bone tissue engineering applications; however, their inadequate 3-dimensionality and poor mechanical properties are among the concerns for their use as bone substitutes. In this study, pullulan (P) and cellulose acetate (CA), two polysaccharides, were electrospun at various P/CA ratios (P-80/CA(20), P-50/CA(50), and F-20/CA(80)%) to develop 3D fibrous network. The scaffolds were then crosslinked with trisodium trimetaphosphate (STMP) to improve ...
Crosslinked polymer gels for boron extraction derived from N-glucidol-N-methyl-2-hydroxypropyl methacrylate
Bicak, N; Ozbelge, HO; Yılmaz, Levent; Senkal, BF (Wiley, 2000-03-24)
Glycidyl methacrylate was reacted in 2-methyl pyrrolidone solution with N-methyl-D-glucamine (NMG) to produce N-D-glucidol, N-methyl-2-hydroxy propyl methacrylate (GMHP). The reaction proceeded exclusively via ring opening of the oxirane. The resulting vinyl monomer was a waxy product and soluble in water, ethanol, methanol, DMF, and NMP. Copolymerization of GMHP with N,N'-tetraallyl piperazinium dichloride by the inverse suspension method (water in oil), using a toluene/chloroform (3:1) mixture as continuo...
Crosslinked polyDADMAC gels as highly selective and reusable arsenate binding materials
Pirgalioglu, Saltuk; Ozbelge, Tulay A.; Özbelge, Hilmi Önder; Bicak, Niyazi (2015-02-15)
High porosity cationic hydrogels synthesized via crosslinking co-polymerization of diallyldimethylammonium chloride (DADMAC) with N,N'-tetraallylpiperaziniumdichloride (TAP) showed high affinity towards arsenate anions over a wide pH range within notably short periods. Batch tests indicated that poly(DADMAC) hydrogels removed 99% of the arsenate anions from aqueous solutions at pH 6-10 and exhibited a maximum arsenic removal capacity of 0.12 g arsenic per gram of hydrogel. DADMAC hydrogels performed well at...
Crosslinking of Trimethylene Carbonate and D,L-Lactide (Co-) Polymers by Gamma Irradiation in the Presence of Pentaerythritol Triacrylate
Bat, Erhan; Feijen, Jan; Grijpma, Dirk W. (Wiley, 2011-07-07)
High-molecular-weight (co) polymers of trimethylene carbonate and D, L-lactide are efficiently crosslinked using PETA during gamma irradiation. Form-stable networks with gel contents of 86 +/- 5 to 96 +/- 1 are obtained from non-crystalline (co) polymers. Glass transition temperatures and elastic moduli of the networks can be varied by adjusting the copolymer composition. The PETA-containing (co) polymer networks are not cytotoxic. Upon incubation in macrophage cultures for 14 d, all (co) polymer films and ...
Crosslinked DADMAC polymers as cationic super absorbents
Korpe, Sinan; Erdogan, Baris; Bayram, Göknur; Özgen, Serkan; Uludağ, Yusuf; Bicak, Niyazi (Elsevier BV, 2009-09-01)
Loosely crosslinked cationic polyelectrolytes (polyquats) with super-water-sorption abilities are presented, for the first time. Hydrogels obtained by radically initiated copolymerization of N,N-diallyl, N,N-dimethyl ammonium chloride (DADMAC) with N-vinyl 2-pyrrolidone (NVP) in presence of N,N,N',N'-tetraallyl piperazinium dichloride (TAP) as crosslinker showed reasonably high equilibrium swelling ratios, as high as those for poly(acrylic acid)-based super absorbents.
Citation Formats
D. H. Atila, D. Keskin, and A. Tezcaner, “Crosslinked Pullulan Cellulose Acetate Electrospun Scaffolds for Bone Tissue Engineering,” 2015, Accessed: 00, 2021. [Online]. Available: