Encylopedia of Polymer Applications

2018-01-01
Söylemez, Saniye
Kesik, Melis
Toppare, Levent Kamil

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INTEGRATIVE NETWORK MODELLING OF DRUG RESPONSES IN CANCER FOR REVEALING MECHANISM OF ACTION
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Classification of cancer drugs is crucial for drug repurposing since the cost and innovation deficit make new drug development processes challenging. Heterogeneity of cancer causes drug classification purely based on known mechanism of action (MoA) and the list of target proteins to be insufficient. Multi-omic data integration is necessary for a systems biology perspective to understand molecular mechanisms and interactions between cellular entities underlying the disease. This study integrates drug-target ...
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Citation Formats
S. Söylemez, M. Kesik, and L. K. Toppare, “Encylopedia of Polymer Applications,” 2018, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/81895.