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Magnetic PAMAM Dendrimers for Targeted Gemcitabine Delivery
Date
2015-11-27
Author
Maryam, Parsian
Pelin, Mutlu
Yalçın Azarkan, Serap
Tezcaner, Ayşen
Gündüz, Ufuk
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https://hdl.handle.net/11511/83518
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Antitumor activity of Gemcitabine, a nucleoside analogue, has been reported in a variety of human tumors, including breast cancer in both experimental and clinical studies. Conventional chemotherapeutic agents are unspecifically distributed all over the body where they affect both cancerous and normal cells. They cause major systemic toxicities and drug resistance, which also restricts drugs therapeutic efficacy. Recent advances in nanotechnology have explored new targeting strategies for enhancing intra-tu...
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P. Maryam, M. Pelin, S. Yalçın Azarkan, A. Tezcaner, and U. Gündüz, “Magnetic PAMAM Dendrimers for Targeted Gemcitabine Delivery,” 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/83518.