Antibacterial Polyhydroxybutyrate (PHB) Membranes for Guided Bone Regeneration

Karahaliloğlu, Zeynep
Ercan, Batur
Taylor, Erik
Chung, Stanley
Denkbaş, Emir Baki
Webster, Thomas
Society for Biomaterials Annual Meeting and Exposition 2014 (16 - 19 Nisan 2014)


Antibacterial Nanostructured Polyhydroxybutyrate Membranes for Guided Bone Regeneration
Karahaliloglu, Zeynep; Ercan, Batur; Taylor, Erik N.; Chung, Stanley; DENKBAŞ, EMİR BAKİ; Webster, Thomas J. (2015-12-01)
The principle of guided bone regeneration (GBR) in orthopedic, cranio-maxillofacial and dental tissue engineering applications is to create a secluded space for the treatment of large bone defects while excluding fibrous connective tissue formation at the defect area. In dental surgeries, a GBR membrane is placed near the dental implant in post-extraction sockets to grow new bone at the implant site, along with inhibiting infection due to the microbial nature of the mouth flora. Poly[(R)-3-hydroxybutyric ac...
Antibacterial properties and osteoblast interactions of microfluidically synhtesized chitosan – spion composite nanoparticles under external static magnetic field
Kafalı, Melisa; Ercan, Batur; Erdem, Emine Yegan; Department of Metallurgical and Materials Engineering (2022-8-18)
In this research, a multistep microfluidic reactor was used to fabricate chitosan superparamagnetic iron oxide composite nanoparticles (Ch - SPIONs) to develop antibacterial agents that can be targeted to infection foci and visualized with magnetic resonance imaging. Monodispersed Ch – SPIONs had an average particle size of 8.8 ± 1.2 nm with a magnetization value of 32.0 emu/g. These nanoparticles were used to fight against Staphylococcus aureus (S. aureus) and Pseudomonas aeruginosa (P. aeruginosa), which ...
Antimicrobial aptamers for detection and inhibition of microbial pathogen growth
Ozalp, Veli Cengiz; Bilecen, Kivanc; Kavruk, Murat; Öktem, Hüseyin Avni (Future Medicine Ltd, 2013-03-01)
Discovery of alternative sources of antimicrobial agents are essential in the ongoing battle against microbial pathogens. Legislative and scientific challenges considerably hinder the discovery and use of new antimicrobial drugs, and new approaches are in urgent demand. On the other hand, rapid, specific and sensitive detection of airborne pathogens is becoming increasingly critical for public health. In this respect affinity oligonucleotides, aptamers, provide unique opportunities for the development of na...
Antimicrobial modifications of poly(ether sulfone) membrane
Doğru, Esra Nur; Akdağ, Akın; Çulfaz Emecen, Pınar Zeynep; Department of Polymer Science and Technology (2016)
Fouling on a membrane is one of the major problems of liquid filtration systems. To solve this problem, physical treatments and modifications are applied on membranes. Biofouling is the most severe form of fouling, which is due to biofilms of microorganisms in a matrix of extracellular polymers they secrete. Biofilm formation has been attacked by periodic cleaning of membrane, disinfection of feed, and surface modification. In this study, we proposed an antimicrobial surface modification to prevent biofilm ...
Antibacterial Chitosan and Heparin Modified Polyurethane Surfaces
Kara, Filiz; Aksoy, Eda Ayşe; Hasırcı, Nesrin; Aksoy, Serpil (null; 2015-10-22)
Citation Formats
Z. Karahaliloğlu, B. Ercan, E. Taylor, S. Chung, E. B. Denkbaş, and T. Webster, “Antibacterial Polyhydroxybutyrate (PHB) Membranes for Guided Bone Regeneration,” presented at the Society for Biomaterials Annual Meeting and Exposition 2014 (16 - 19 Nisan 2014), Denver, Colorado, USA, 2014, Accessed: 00, 2021. [Online]. Available: