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The Effects of Drug Resistant MCF7 Sublines on Cellular Proliferation and Gene Expression Pattern of Drug Sensitive MCF7 Cells
Date
2015-06-09
Author
Esin Gülce, Seza
Laçin, Yapındı
Çağrı, Urfalı Mamatoğlu
Gündüz, Ufuk
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The resistance of tumor cells to structurally and functionally unrelated drugs is named as multidrug resistance (MDR) [1]. Tumors consist of cells with different genetic make-ups. Due to the tumor heterogeneity, some of the cells in a tumor could be drug-sensitive whereas the others could be intrinsicly resistant or acquire resistance during the course of chemotherapy. This heterogenous nature of tumors could cause the failure in chemotherapy. The aim of the current study is to investigate the effects of drug-resistant MCF7 sublines on drug-sensitive MCF7 cells.
URI
https://hdl.handle.net/11511/86720
Conference Name
11th International Symposium on Pharmaceutical Sciences, 9 - 11 Haziran 2015
Collections
Graduate School of Natural and Applied Sciences, Conference / Seminar
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S. Esin Gülce, Y. Laçin, U. M. Çağrı, and U. Gündüz, “The Effects of Drug Resistant MCF7 Sublines on Cellular Proliferation and Gene Expression Pattern of Drug Sensitive MCF7 Cells,” presented at the 11th International Symposium on Pharmaceutical Sciences, 9 - 11 Haziran 2015, Ankara, Türkiye, 2015, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/86720.
