Macrophage mediated Biodegradation of Gamma Irradiated Poly trimethylene carbonate

Date

2009-09-07

Author

Bat, Erhan
Feijen, Jan
Grijpma, Dirk W

Metadata

Show full item record

Item Usage Stats

71
views

0
downloads

URI

https://hdl.handle.net/11511/88161

Collections

Unverified, Conference / Seminar

Suggestions

OpenMETU
Core

Macrophage-mediated erosion of gamma irradiated poly(trimethylene carbonate) films Bat, Erhan; Feijen, Jan; Grijpma, Dirk W. (2009-08-01) A macrophage culture model was used to investigate the erosion of gamma irradiated poly(trimethylene carbonate) (PTMC) films. When the PTMC films were incubated in the culture medium, but physically separated from the cells by a membrane, no erosion occurred. In contrast, when the J774A macrophages were directly cultured on PTMC films, they adhered to the films and were found to have eroded the polymer surface. Macrophages adhered to gamma irradiated poly(E-caprolactone) (PCL) controls as well, but to a les...
Microphase Separation of Phenylene Oligomers with Polymeric Side Chains: A Dissipative Particle Dynamics Study Yıldırım, Erol; Kenarli, Burcu; Demirel, A. Levent (Wiley, 2011-06-22) The microphase-separated morphologies of p-phenylene oligomers with POx, PCL, PS, and PEO side chains are studied using DPD simulations. It is shown that the microphase-separated morphologies depend significantly on the degree of chemical incompatibility between the components as indicated by the Flory-Huggins interaction parameters. The good agreement of the microphase separated morphologies as simulated by DPD with the experimentally determined thin film morphologies suggests that DPD can produce convinci...
Macroporous poly(3-hydroxybutyrate-co-3-hydroxyvalerate) matrices for bone tissue engineering Kose, GT; Kenar, H; Hasırcı, Nesrin; Hasırcı, Vasıf Nejat (2003-05-01) Macroporous poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) (PHBV) matrices were prepared after solvent evaporation and solute leaching. PHBV solutions with different concentrations were prepared in chloroform: dichloromethane (1:2, v/v). In order to create a matrix with high porosity and uniform pore sizes, sieved sucrose crystals (75-300 or 300-500 mum) were used. PHBV foams were treated with rf-oxygen plasma to modify their surface chemistry and hydrophilicity with the aim of increasing the reattach...
Biopolymer based micro/nanoparticles as drug carriers for the treatment of skin diseases Eke, Gözde; Hasırcı, Vasıf Nejat; Hasırcı, Nesrin; Department of Micro and Nanotechnology (2011) Controlled drug delivery systems are becoming increasingly interesting with the contribution of nanotechnology. In the case of transdermal applications the greatest limitation is the highly impermeable outermost layer of the skin, the stratum corneum. One promising method of controlled transdermal drug delivery of the skin therapeutics is the use of nanoparticles as carriers. Encapsulation of the drug, as opposed to classical topical application of creams or emulsions, allows the drug to diffuse into hair f...
Bioprocess design parameters for beta-lactamase production by Bacillus species Çelik, Eda; Çalık, Pınar; Department of Chemical Engineering (2003) In this study, the effects of bioprocess design parameters on β-lactamase production were systematically investigated using wild type Bacillus species. For this purpose, the research programme was carried out in mainly four parts. Initially, potential β-lactamase producers were screened and Bacillus licheniformis ATCC 25972, a constitutive β-lactamase producer, was selected. Next, the effects of bioprocess medium components, i.e., carbon sources (glucose, fructose, sucrose, citric acid and glycerol), inorga...

Citation Formats

E. Bat, J. Feijen, and D. W. Grijpma, “Macrophage mediated Biodegradation of Gamma Irradiated Poly trimethylene carbonate,” 2009, Accessed: 00, 2021. [Online]. Available: https://hdl.handle.net/11511/88161.