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Numerical and experimental investigation of acoustophoretic microfluidic devices
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12626004.pdf
Date
2021-1
Author
Şahin, Mehmet Akif
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Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License
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Acoustophoresis is one of the techniques to manipulate suspended particles to intended positionsin continuous flow. In this study, a numerical simulation methodologythatcouples electro-mechanic, solid,and acoustic domains in 3Dhas been developedfor acoustofluidic chips. Numerical investigation of design and operation parameters'effectswere performedin terms of performance metrics. The simulation model was usedfor further analysis to understand the effects of manufacturing and assembly errors on acoustophoretic performance.The combined effect of chip dimensions on particle separation was investigated using the Monte Carlo approach.Acoustophoretic chips made of silicon, glass, and acrylic were fabricated and compared in terms of microparticlefocusingperformance.Even though the acrylic chip is more tolerant to thedimensional and manufacturingvariations, silicon and glass based chips were able tofocusthe microparticles better than the acrylic chip.
Subject Keywords
Acoustophoresis
,
Particle manipulation
,
Numerical modelling
,
Monte carlo
,
Sensitivity analysis
,
Akustoforez
,
Parçacık manipülasyonu
,
Sayısal modelleme
,
Hassasiyet analizi
URI
https://hdl.handle.net/11511/88681
Collections
Graduate School of Natural and Applied Sciences, Thesis
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M. A. Şahin, “Numerical and experimental investigation of acoustophoretic microfluidic devices,” M.S. - Master of Science, Middle East Technical University, 2021.
