The synthesis of 2-substituted epichlorohydrins and their reactions

Özgül, Emine


The enantioselective synthesis of 2-indolyl-1-nitro derivatives and BODIPY dyes in the presence of chiral bifunctional squaramide organocatalysts
Dündar, Esra; Tanyeli, Cihangir; Department of Chemistry (2022-8)
In our research group, chiral bifunctional squaramides with different basic units have been synthesized and evaluated in various asymmetric reactions. To test the catalytic activity of organocatalysts, Friedel-Crafts alkylation of indoles with nitroolefins was selected as a model reaction in the first part of the study. 19 different 2-indolyl-1-nitro derivatives were synthesized with up to >99% ee in the presence of sterically encumbered tert-butyl substituted squaramide/quinine. Besides, 2-adamantyl squara...
The cathodic cleavage of aryl tetrazole ethers.
Toppare, Levent K; Akbulut, Ural; Department of Chemistry (1982)
The reaction of alkenes with AgNO2/TMSCl: The synthesis of 1,2,5-oxadiazole-2-oxides (Furoxans) via nitroso nitrates
Demir, Ayhan Sıtkı; Findik, H (Bentham Science Publishers Ltd., 2005-11-01)
The reaction of AgNO2/TMSCl with olefins affords nitrosonitrate, which arc converted into (alpha-nitroximes in good yield. Both nitrosonitrate and nitroximes are converted with acids into furoxane in high yield. The reaction of AgNO2 with TMSCl furnished first N2O3 and hexamethylsiloxane. The nitroso nitrates are obtained by addition of N2O3 to the olefines.
The synthesis of hydroxymethyl containing cyclitol derivatives
Kaya, Nihal; Balcı, Metin; Department of Chemistry (2009)
Cyclitols have attracted a great deal of attention in recent years because of diverse biological activities exhibited by them and also synthetic usefulness in the synthesis of other natural compounds or pharmaceuticals. The presence of hydroxymethyl groups in many cyclitols units building natural products is also attracting a remarkable attention. In this study, novel synthetic strategies leading to cyclitol derivatives including hydroxymethyl groups were investigated and the syntheses of bis-homoinositol d...
The synthesis of unusual isocoumarin derivatives: the chemistry of homophthalic acid
Ozcan, Sevil; Sahin, Ertan; Balcı, Metin (Elsevier BV, 2007-03-19)
Homophthalic acid was reacted with thionyl chloride/DMF and ethyl chloroformate/NEt3 in the presence and absence of NaN3. In all cases completely different isocoumarin derivatives were obtained. These unusual isocournarin derivatives were characterized and their mechanism of formation is discussed.
Citation Formats
E. Özgül, “The synthesis of 2-substituted epichlorohydrins and their reactions,” Middle East Technical University, 1994.